Program Engineer Salary in Connecticut, USA

Provides engineering design services for assigned projects from the time it is assigned until the time it is commissioned in the field.ESSENTIAL FUNCTIONS: Produce required documentation for fabrication purposes by researching custom specifications, industry standards and evaluating manufacturing and assembly methods and materials. Provides engineering information by answering questions and requests. Resolves differences between design and fabrication requirements by making determinations such as modifying design verses sending parts back to the vendor. Works with Test in troubleshooting designs and completing projects by freely and openly collaborating with Test Technicians. Maintains Product and company reputation by complying with applicable regulations and standards. Expected to work with assistance from other sources such as engineering, project management, purchasing etc... With more experience, limited assistance is expected. ADDITIONAL RESPONSIBILITIES: (Electrical) Evaluates assigned projects by designing and conducting research around custom specifications and applying degreed level knowledge of electricity and materials. Releases projects to manufacturing by assembling bill of materials, generating electrical schematics, point to point interconnects and developing application specific programs and description of operation. Maintains drawing and program revisions by issuing Engineering Change Notices. May be required to represent assigned engineering functions during Factory Witness Tests. Assumes additional responsibilities as assigned. Some Travel may be required when experience is obtained. MINIMUM QUALIFICATIONS: Strong Work Ethic: Self-motivated and dedicated to completing the task at hand regardless of setbacks. Positive Attitude: Focuses on solutions and opportunities when confronted with difficult challenges. Flexibility: Adapts to new situations and readily accepts new challenges when the need arises. Stability: Remains calm under pressure. Coachable: Open to learning new ideas and able to handle criticism. Specific Knowledge (Electrical): Thorough understanding of the fundamental concepts involved in electrical circuit design, Power Systems, Digital Logic and basic Protective Relaying applications. AutoCAD, Word Processing, Spreadsheets, File Management Software, Jobscope/JDE, Promis-E Software, Ladder Logic and GE Proficy Software. Awareness and understanding of applicable codes, including NEC, NFPA110, UL508, UL891, UL1008 and UL1558. EDUCATION and/or EXPERIENCE (Electrical): Education: 4 year engineering degree in Electrical/Computer Engineering. Experience: Three or more years of professional experience in OEM design activities, PLC or script-based programming, meeting schedules and providing technical support. Why us?Schneider Electric is leading the digital transformation of energy management and automation. Our technologies enable the world to use energy in a safe, efficient and sustainable manner. We strive to promote a global economy that is both ecologically viable and highly productive.€25.7bn global revenue137 000+ employees in 100+ countries45% of revenue from IoT5% of revenue devoted for R&DYou must submit an online application to be considered for any position with us. This position will be posted until filledIt is the policy of Schneider Electric to provide equal employment and advancement opportunities in the areas of recruiting, hiring, training, transferring, and promoting all qualified individuals regardless of race, religion, color, gender, disability, national origin, ancestry, age, military status, sexual orientation, marital status, or any other legally protected characteristic or conduct. Concerning agencies: Schneider Electric does not accept unsolicited resumes and will not be responsible for fees related to such.Provides engineering design services for assigned projects from the time it is assigned until the time it is commissioned in the field.ESSENTIAL FUNCTIONS: Produce required documentation for fabrication purposes by researching custom specifications, industry standards and evaluating manufacturing and assembly methods and materials. Provides engineering information by answering questions and requests. Resolves differences between design and fabrication requirements by making determinations such as modifying design verses sending parts back to the vendor. Works with Test in troubleshooting designs and completing projects by freely and openly collaborating with Test Technicians. Maintains Product and company reputation by complying with applicable regulations and standards. Expected to work with assistance from other sources such as engineering, project management, purchasing etc... With more experience, limited assistance is expected. ADDITIONAL RESPONSIBILITIES: (Electrical) Evaluates assigned projects by designing and conducting research around custom specifications and applying degreed level knowledge of electricity and materials. Releases projects to manufacturing by assembling bill of materials, generating electrical schematics, point to point interconnects and developing application specific programs and description of operation. Maintains drawing and program revisions by issuing Engineering Change Notices. May be required to represent assigned engineering functions during Factory Witness Tests. Assumes additional responsibilities as assigned. Some Travel may be required when experience is obtained.

Job Title Operating Engineer Job Description Summary Responsible to ensure the efficient operation and maintenance of mechanical, electrical and plumbing equipment and systems for the assigned property(s). Responsibilities include (but are not limited to) maintaining a clean and safe working environment, performing rounds, conducting routine assessments, performance of day-to-day preventive and corrective maintenance, painting, and housekeeping for assigned properties Job Description ESSENTIAL FUNCTIONS AND RESPONSIBILITIES• Perform all plumbing, electrical, or HVAC requirements of the building(s)• Maintain heating equipment, chillers (air and/ or water cooled), DX units, pumps, cooling towers, fan coil units, VAV, and air distribution systems, etc.• Monitor and adjust all mechanical/pneumatic equipment, steam stations, control gauges, distributor panels, valves, thermostats, diffusers, and other equipment necessary to provide a comfortable environment for the buildings• Verify field conditions and perform any necessary repairs or adjustments• Monitor Energy Management• Repair doors, ceilings, hand railings, and floors and other general repairs, adjustments and installations about the property• Perform repairs to plumbing fixtures (water closets, urinals, flush valve assemblies, lavatories, etc.)• Perform preventive maintenance duties in accordance with C&W standards, building protocol, manufacturer recommendations and industry best practices. including changing filters, cleaning coils, flushing condensers, punching tubes, greasing fan, pump and motor bearings as required, inspecting and adjusting belts, replacing motor bearings, aligning pulleys and shafts, monitor condenser, chilled, heating and secondary water chemical treatment and its associated feed equipment, clean and maintain cooling towers, and perform annual inspections and other scheduled routines as directed.• Inspect engine room equipment, fan room equipment, cooling tower, all motors, house pumps, electric rooms, back-up generator, fire pump(s), sump pump(s), and ejector pumps. Replace lamps, light fixtures, reinstall or replace signage, verify rooms are clean and clear of obstructions and debris• Check for properly operating emergency exit signs and lights and ensure free and clear access to emergency stairs and exits. Perform additional fire and life safety inspections as per NFPA and local jurisdiction, C&W standards, building protocol and as directed by superiors and property management• Document and report activities to supervisor• Respond immediately to emergency situations (fire, evacuation, equipment failure, etc.) and customer concerns• Comply with all applicable codes, regulations, governmental agency, and company directives as relates to building operations and practice safe work habits• Complete all required C&W Safety Training as scheduled annually• Comply with C&W Uniform Dress Code while working and maintain a neat and clean appearance while on the property at times other than working hoursKEY COMPETENCIES• Technical Proficiency• Initiative• Flexibility• Multi-Tasking• Sense of Urgency• Knowledge of BMS & Pneumatic controlsIMPORTANT EDUCATION• High School Diploma of GED Equivalent• Graduate of apprentice program or trade school preferred• S2 certificationIMPORTANT EXPERIENCE• 5+ years of related work experience in operating mechanical, electrical, and plumbing systems in a commercial property settingADDITIONAL ELIGIBILITY QUALIFICATIONS• Appropriate license/permit for trade as may be required, i.e. Journeyman or Master Electrician License or City Licenses, such as Refrigeration Certificate of Fitness, High Pressure Boiler License, High Pressure Steam Operator, etc.)• May be required to have certification as a Universal Technician for CFC's depending on market licensure requirements• Possess and maintain a valid driver's license and good driving record with periodic checks (where applicable)• Basic Computing Skills in Outlook, Excel & Word• Experience in operation, maintenance and basic repair of HVAC, boilers, heaters, pumps, refrigerant systems, compressors, water systems, etc.• Knowledgeable in energy management systems, techniques and operations.• Thorough knowledge in all building systems operations, maintenance and repair.May be only maintenance staff member on duty during certain shifts; may be required to work extended periods of time without relief when responding to priority/emergency situations (including overtime type assignments); may require shift work and/or on call dutiesWORK ENVIRONMENTThis job operates in a professional office environment. This role routinely uses standard office equipment such as computers, phones, photocopiers, filing cabinets and fax machines. Regularly required to travel outside between properties in varying weather conditions. 8AM-4:30PM ShiftPHYSICAL DEMANDSThe physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job.• Must have ability to stoop, stand, climb, frequently lift a minimum of 50 lbs. of equipment (pumps, tools, ladders) and safely install rigging/lifting devices• Regularly required to crouch and reach to install/move equipment by bending forward at the waist or by bending legs and spine• Involves movement between departments, floors, and properties to facilitate work• Ability to speak clearly so others can understand you• Ability to read and understand information presented orally and in writing• Regularly required to utilize vision abilities, allowing reading of printed material, drawings, and schematicsAAP/EEO STATEMENTC&W provides equal employment opportunity to all individuals regardless of their race, color, creed, religion, gender, age, sexual orientation, national origin, disability, veteran status, or any other characteristic protected by state, federal, or local law. Further, the company takes affirmative action to ensure that applicants are employed and employees during employment are treated without regard to any of these characteristics. Discrimination of any type will not be tolerated.OTHER DUTIESThis job description is not designed to cover or contain a comprehensive list of activities, duties or responsibilities that are required of the employee. Other duties, responsibilities and activities may change or be assigned at any time with or without notice.Cushman & Wakefield provides equal employment opportunity. Discrimination of any type will not be tolerated. Cushman & Wakefield is an Equal Opportunity / Affirmative Action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability, protected veteran status or any other characteristic protected by state, federal, or local law.In compliance with the Americans with Disabilities Act Amendments Act (ADAAA), if you have a disability and would like to request an accommodation in order to apply for a position at Cushman & Wakefield, please call the ADA line at 1-888-365-5406 or email [email protected] . Please refer to the job title and job location when you contact us.

Are you ready to join Connecticut Innovation's vibrant community of innovators? Connecticut Innovations ("CI") is Connecticut's strategic venture capital arm, and we are passionate about serving our portfolio of 220+ companies across various industries, with strengths in life sciences, technology, and climate tech. Come join one of our quickly growing portfolio companies, Enko!At Enko we believe that to create the future the world wants, we need to change the way the world grows. Our goal is not just to create something better, but to play a part in something bigger. Enko discovers and develops novel products for farmers to protect their crops from pests and disease.Our agricultural invention platform, Enkompass™, uses A.I. and machine learning to create more effective ways of finding and selecting the right treatments for the right targets. Led by a team of proven scientists, entrepreneurs, and industry veterans, Enko's innovative science, agile design, and discovery of new modes of action is producing next-generation crop protection solutions that will overcome the critical challenges facing industry. The industry has taken notice, and we have active projects with many key industry players...with more to come!Enko is searching for a highly collaborative, solutions-oriented Software Engineer to join their quickly growing computational science team to specifically to help build unique datasets, AI models, and the infrastructure to support them.What You'll DoYour main objective will be to develop internal tools, data products, and infrastructure that will enhance the productivity of our small molecule discovery pipeline. You will be a key contributor to the direction and execution of our software infrastructure, and to making technical decisions that advance our AI and data products. You will have influence in the continued development of a culture of innovation and empowerment as a valued technical expert.This will be a hybrid role, at our HQ and research facility in Mystic, CT. The successful candidate must be very comfortable working in a fast-paced environment with demonstrated ability to juggle competing tasks and demands. This role represents a great opportunity to utilize scientific, technical, and interpersonal skills:Build software tools to support the Company's computational chemistry efforts including molecular design, chem informatics, AI-based predictive systems, simulation and virtual screening.Architect cloud infrastructure for handling large datasets and computational needs efficiently and easily.Apply expertise to enable training and validation of machine learning models using data from multiple sources, including DEL screening experiments, to rapidly and cost effectively discover and optimize chemistries.Collaborate closely across the company to explore ways to accelerate the discovery and development of novel small molecules aligned with the company's strategic goals.About YouYou hold an advanced degree in a STEM discipline.You have a minimum of 3 years of post-degree experience in a lab environment or related industry.You have previous Individual contributor experience in both data engineering and machine learning engineering for deep learning models, preferably in a scientific application.You care about building clean code and are passionate about continuous development of your technical skillset. You have previously written test scripts and SQL queries.You have experience building and maintaining scalable APIs.You possess the ability to move beyond packaged software to prototype and implement innovative ideas.You love to build relationships and have an eagerness to collaborate across disciplines and quickly learn new domain knowledge. You are inquisitive and believe that broad curiosity helps to generate process improvements. Why Work at Enko?Our products address a $70 billion core market focused on crop health with expansion into adjacent markets worth $300+ billion.We have $150 million in capitalization, with $80 million raised as part of a Series C in December 2022 Our global investors include Anterra Capital, Nufarm, the Bill & Melinda Gates Foundation, Eight Roads Ventures, Finistere Ventures, Rabo Food & Agri Innovation Fund, Novalis LifeSciences, Syngenta, TaherGozal, Germin8 Ventures, TO Ventures Food, Endeavor8, Connecticut Innovations, Silver Blue LLC, and Alumni Ventures Group.We have over 40 novel pipeline programs and 5 strategic partnerships announced, including with Syngenta and BayerOur headquarters and research facility in Mystic, CT has 90,000 square feet of state-of-the-art labs and computer-controlled greenhouses built for pre-field experimentation and scale.Enko is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.

ABOUT THE TEAM Shaner Hotels has an amazing opportunity at our Residence Inn Norwalk located in beautiful downtown Norwalk. This 102-room modern Residence Inn is just a short walking distance from the trendy SoNo, which is filled with many dining, shopping, and entertainment opportunities for our guests.ABOUT US Shaner Hotel Group Shaner Hotels is one of the foremost award-winning hospitality owner-operators and management companies in the hospitality industry. Our current portfolio consists of over 65 full-service, select-service, extended-stay and resort properties with more than 7,500 rooms in 14 states and four countries. We partner with the top Hospitality Brands including independent locations as well. We provide a variety of services for investors, hotel owners and brands-including hotel development, design and construction, e-commerce, and revenue management. You can find out more by visiting our website, www.shanercorp.com!JOB DESCRIPTION Be available to work a flexible schedule, including weekends, holidays, and varied shifts, as required to meet the needs of the Company's business operations. Delegate daily work assignments and review priorities and special projects. Schedule and perform work in accordance with preventive maintenance program in rooms, coordinating with the Rooms Division Department. Ensures final inspection of all engineeringrelated work and execution of all work orders. Performs engineering staff functions whenever necessary. Ensures all safety equipment is in compliance and working order with federal quarterly/annual inspections to city, state and codes. Maintain knowledge of hotel safety procedures and ensure application of such. Handle chemicals for designated uses/surfaces, according to hotel requirements. Perform emergency equipment and machinery repair as needed. Maintain the proper use, cleaning, maintenance, and storage of all tools. Exercise safety precautions when working on equipment (use of safety signs, etc.). Maintains the engineering department's annual budget. Carries out supervisory responsibilities that includes interviewing, hiring, and training employees; planning, assigning, and directing work; appraising performance; rewarding and disciplining employees; addressing complaints and resolving problems. Responsibilities Responsible for all aspects of the Engineering department to include the proper operation, maintenance, preventive maintenance, and repair of all heating, ventilation, refrigeration, and mechanical equipment. Develop, coordinate, and monitor a maintenance program to ensure the safety, security and comfort of all staff and guests. Assigned responsibility of Safety Committee Chairperson. Supervise, train and manage all Engineering staff. Qualifications High school graduate or equivalent; college degree or vocational training a plus. Any building trade license/certificate from the state of hotel's operation preferred. Ability to satisfactorily communicate with guests, management, and co-workers to their understanding. Bilingual English/Spanish a plus. Minimum two years' experience as a hotel maintenance engineer. Supervisory experience preferred. Valid driver's license and clean driving record. Knowledge of all mechanical equipment critical to the operation of the building. Working knowledge of repair and maintenance regarding health codes; plumbing codes; plant equipment; electrical codes; architectural codes; structural codes; blueprints and wiring/plumbing schematics; building code improvement; mechanical and electrical/safety systems construction; national/local fire codes; proper chemical handling and disposal; power and hand tools, meters, etc. as it relates to the technical trades; local mechanical codes; OSHA codes and best practices. Ability to read and interpret documents such as safety rules, operating and maintenance instructions, and procedure manuals. Ability to interpret manufacturer's literature for installation, preparation, use and upkeep of various materials and products used throughout the property. Ability to perform assigned duties with attention to detail, speed, accuracy, follow-through, courtesy, cooperativeness and work with a minimum of supervision. Ability to endure abundant physical movements in carrying out job duties. Ability to enforce hotel's standards, policies and procedures with staff. Ability to troubleshoot and use alternatives in emergency situations. Ability to handle potentially hazardous chemicals. Ability to maintain confidentiality of hotel guests and pertinent hotel information.

JOB DESCRIPTION About Us Chubb is a world leader in insurance. With operations in 54 countries, Chubb provides commercial and personal property and casualty insurance, personal accident and supplemental health insurance, reinsurance, and life insurance to a diverse group of clients. The company is distinguished by its extensive product and service offerings, broad distribution capabilities, exceptional financial strength, underwriting excellence, superior claims handling expertise and local operations globally. At Chubb, we are committed to equal employment opportunity and compliance with all laws and regulations pertaining to it. Our policy is to provide employment, training, compensation, promotion, and other conditions or opportunities of employment, without regard to race, color, religious creed, sex, gender, gender identity, gender expression, sexual orientation, marital status, national origin, ancestry, mental and physical disability, medical condition, genetic information, military and veteran status, age, and pregnancy or any other characteristic protected by law. Performance and qualifications are the only basis upon which we hire, assign, promote, compensate, develop and retain employees. Chubb prohibits all unlawful discrimination, harassment and retaliation against any individual who reports discrimination or harassment. Job Description We are seeking a highly skilled and motivated Data Engineer with experience in Master Data Management (MDM) technology to join our Global Data Engineering Organization. As a Data Engineer, the individual will be responsible for the design, development, and enrichment of our MDM solutions, ensuring accurate and reliable master data across the enterprise. The Ideal candidate should be results-oriented and has an ambition to contribute to the success of Master Data program. The successful candidate will be self-motivated, creative, and will be able to independently contribute to our MDM strategic initiative. Must have hand-on-experience with master data, ETL/ELT technologies, Azure platform & SQL. Responsibilities Design & support the MDM data architecture for large-scale data project. Collaborate with cross-functional teams to understand business requirements and design master data solution. Implement data models, define data integration workflows, and configure MDM tools to meet business needs. Create and maintain technical design documentation to ensure consistency and standardization across data platforms related to MDM solution. Develop data integration pipelines to extract, transform, and load data from various sources into the MDM system. Leverage SaaS MDM platform & adhere to design principles to enhance MDM capabilities and efficiency. Implement data stewardship processes and workflows to maintain data integrity and enforce data management policies. Perform core MDM functionalities such as Match/Merge, Survivorship, Hierarchy Management and External Match Contribute to Data Modelling & Data Management activities. Work in an Agile development environment and utilize DevOps, CI/CD (Jenkins, Jira, Terraform, Ansible etc.) processes. Must love coding - prepare to spend more than 80% of the time on hands-on development with available data technologies. Work closely with business users, data stewards, and IT teams to identify and resolve Master data-related issues. QUALIFICATIONS QualificationsABOUT US Chubb is a world leader in insurance. With operations in 54 countries, Chubb provides commercial and personal property and casualty insurance, personal accident and supplemental health insurance, reinsurance, and life insurance to a diverse group of clients. The company is distinguished by its extensive product and service offerings, broad distribution capabilities, exceptional financial strength, underwriting excellence, superior claims handling expertise and local operations globally. At Chubb, we are committed to equal employment opportunity and compliance with all laws and regulations pertaining to it. Our policy is to provide employment, training, compensation, promotion, and other conditions or opportunities of employment, without regard to race, color, religious creed, sex, gender, gender identity, gender expression, sexual orientation, marital status, national origin, ancestry, mental and physical disability, medical condition, genetic information, military and veteran status, age, and pregnancy or any other characteristic protected by law. Performance and qualifications are the only basis upon which we hire, assign, promote, compensate, develop and retain employees. Chubb prohibits all unlawful discrimination, harassment and retaliation against any individual who reports discrimination or harassment.

This is what you will do: This position will lead research, design and implement scientific studies to enable the drug product (DP) process development, characterization, clinical manufacturing, and commercial validation of parenteral/injectable biologic products. Lead and support execution of stability studies, data processing, compiling and presentation of results supporting late-stage clinical activities as well as preparation for PPQ. Develop a variety of manufacturing unit operations including, drug substance (DS) freeze/thaw, compounding/mixing, sterile filtration, drug product filling of vials/syringes, visual inspection, and DS/DP transportation. A general understanding of protein chemistry and/or the ability to run biopharmaceutical assays in a laboratory is preferred.The role will lead manufacturing technology transfer activities in preparation for DS and DP PPQs, sending/receiving site process gap analysis, process FMEAs (failure mode and effects analysis), change control owner/leader, master batch record review, as well as leading at-scale/full scale process development studies, and authoring protocols, and reports. In addition, will support deviation investigations, change controls, and CAPAs using electronic Quality system. The candidate will also provide clinical and commercial manufacturing site support including but not limited to periodic meetings, action item owner, and in-person on-site manufacturing support. Interact regularly with multi-functional staff from Analytical Sciences & Quality Control, Drug Substance Process Development, Manufacturing Technical Services, Quality Assurance, and/or CMC Regulatory Affairs to support progress of the program and preparation of source documentation supporting BLA.You will be responsible for: Own the design and implement studies for Alexion pharmaceuticals' clinical drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sitesLead progression of projects with multi-functional collaborators, as well as understand the implications of project activities and decisions with minimal directionPrioritizing multiple tasks and projects independently and as part of the teamAuthor SOPs, study protocols and technical reportsParticipate in multi-functional development teams representing Injectable Drug Product DevelopmentMaintain knowledge of current trends in drug product manufacturing processes, manufacturing equipment and single use systems as well as associated global regulatory expectations and scientific principles and theories. Train other peers as assigned in areas of expertiseActively participate in department and team meetings including assuming ownership and delivering on assign action itemsDevelop presentations for meetings with internal and external partnersYou will need to have:Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or relevant Engineering/Life Sciences field with 4+ years of relevant experience or Master's degree with 3+ years of relevant work experienceDedicated initiative to find resolution for technical challengesExcellent interpersonal, collaborative and communication skillsThe duties of this role are conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.We would prefer for you to have:Scientific and practical knowledge of protein biochemistry and/or drug product process developmentPrevious experience in bio-therapeutics development as well as relevant knowledge of cGMP and Quality expectations for PPQs and BLAScientific understanding of protein stability, thermodynamics, mechanism of protein degradation, bio-therapeutics drug formulation development and analytical tools used to test formulations is a plusHigh level proficiency in MS Office software including Word, Excel, Outlook, Visio, and PowerPointExpectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world!AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

This is what you will do: This position will lead research, design and implement scientific studies to enable the drug product (DP) process development, characterization, clinical manufacturing, and commercial validation of parenteral/injectable biologic products. Lead and support execution of stability studies, data processing, compiling and presentation of results supporting late-stage clinical activities as well as preparation for PPQ. Develop a variety of manufacturing unit operations including, drug substance (DS) freeze/thaw, compounding/mixing, sterile filtration, drug product filling of vials/syringes, visual inspection, and DS/DP transportation. A general understanding of protein chemistry and/or the ability to run biopharmaceutical assays in a laboratory is preferred.The role will lead manufacturing technology transfer activities in preparation for DS and DP PPQs, sending/receiving site process gap analysis, process FMEAs (failure mode and effects analysis), change control owner/leader, master batch record review, as well as leading at-scale/full scale process development studies, and authoring protocols, and reports. In addition, will support deviation investigations, change controls, and CAPAs using electronic Quality system. The candidate will also provide clinical and commercial manufacturing site support including but not limited to periodic meetings, action item owner, and in-person on-site manufacturing support. Interact regularly with multi-functional staff from Analytical Sciences & Quality Control, Drug Substance Process Development, Manufacturing Technical Services, Quality Assurance, and/or CMC Regulatory Affairs to support progress of the program and preparation of source documentation supporting BLA.You will be responsible for: Own the design and implement studies for Alexion pharmaceuticals' clinical drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sitesLead progression of projects with multi-functional collaborators, as well as understand the implications of project activities and decisions with minimal directionPrioritizing multiple tasks and projects independently and as part of the teamAuthor SOPs, study protocols and technical reportsParticipate in multi-functional development teams representing Injectable Drug Product DevelopmentMaintain knowledge of current trends in drug product manufacturing processes, manufacturing equipment and single use systems as well as associated global regulatory expectations and scientific principles and theories. Train other peers as assigned in areas of expertiseActively participate in department and team meetings including assuming ownership and delivering on assign action itemsDevelop presentations for meetings with internal and external partnersYou will need to have:Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or relevant Engineering/Life Sciences field with 4+ years of relevant experience or Master's degree with 3+ years of relevant work experienceDedicated initiative to find resolution for technical challengesExcellent interpersonal, collaborative and communication skillsThe duties of this role are conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.We would prefer for you to have:Scientific and practical knowledge of protein biochemistry and/or drug product process developmentPrevious experience in bio-therapeutics development as well as relevant knowledge of cGMP and Quality expectations for PPQs and BLAScientific understanding of protein stability, thermodynamics, mechanism of protein degradation, bio-therapeutics drug formulation development and analytical tools used to test formulations is a plusHigh level proficiency in MS Office software including Word, Excel, Outlook, Visio, and PowerPointExpectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world!Date Posted26-Apr-2024Closing Date30-Jul-2024Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact [email protected]. Alexion participates in E-Verify.AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

This position is responsible for leading the design, development, programming and implementation of new systems and controls for future pharmaceutical manufacturing processes and plant automation systems for full compliance with FDA regulations, reporting directly to the site lead for systems and controls. Support the facility, utility, manufacturing and packaging related control systems. Train, Design, and Troubleshoot controls and instrumentation systems to resolve discrepancies. Lead current and future equipment purchases, while vetting preferred vendors and insourcing contracted labor. Leads through hands on methodology to programming, installation, and configuration of systems. Create design of experiments for testing and execute test strategies, prepare and execute protocols, analyze results using statistical methods, prepare technical reports and write standard operating procedures. Manage project schedules through integrated product teams to coordinate control related activities, validation, Process Engineering, Facilities Engineering, Manufacturing, and/or Quality. Support and perform calibrations. This position is hands-on management leading by doing, training, and supporting teams throughout the organization.Responsibilities:Direct experience with Allen-Bradley Programmable Logic Controllers (PLC) programming, FactoryTalk SE/ME (HMI), Servo drives, ELAU, B&R PLC programming, Zenon SCADA and supporting software is required.Solid understanding of computers, networking and communication protocols used with industrial controllers, along with the ability to troubleshoot equipment problems and perform complex system tests.Knowledge of Rockwell Automation RsLogix5000, Siemens S7 TIA portal, ELAU PLC software, Wonderware InTouch, and Wonderware Industrial Application Server is highly desired.Experience with motion control, Cognex and Keyence vision systems, fieldbus communications (Ethernet/IP, Profibus, DeviceNet, ControlNet etc.), robotics, Kepware software and Safety PLCs is desired.Design, specification, programming, simulation and testing of control systems, utilities systems, and building automation within existing and new facilities for full compliance with FDA regulations.Create proactive plans to ensure all plant Automation, Process, and Robotic Systems have minimized downtime. Analyze, troubleshoot, and create electrical circuitry using schematics and autodesk.Leads and Supports facility, utility, manufacturing and filling/packaging related control systems along with capital projects. Execute with minimal guidance from Director of Systems and Controls Engineer, and lead department control system projects, schedules, and other necessary control system project tasks.Supports facility, utility, future manufacturing and filling/packaging related control systems along with capital projects.Review documentation, methods, equipment, and procedures to improve efficiencies.Domestic and overseas travel to equipment vendor facilities for FAT execution and other project assignments (Utilize life cycle methodologies and standards (GAMP5, S88, S95, 21 CFR Part 11) for the design, development, installation, qualification, and validation of existing and future control systems and building management control systems.Evaluate and select upgrades for legacy equipment to ensure proper part obsolescence initiatives are met.Other duties include, but not limited to, troubleshooting control and instrumentation systems to resolve discrepancies, install automated systems, configure automated systems, develop test strategies, execute test strategies, prepare protocols, execute protocols, prepare technical reports and write standard operating procedures.Develop control systems documentation, SOPs, along with system change controls, IQ, OQ, FAT/SAT/Commissioning, as required, to provide ongoing upgrades and new systems in support for cGMP Manufacturing and Utility control systems.Update and/or produce electrical drawings, control panel layouts, and other technical documentation in support of new or existing control systems.Work cross functionally with Validation, Facilities, Calibration, Manufacturing, Process, and Engineering efforts and other cross functional departments requiring controls related assistance and SME (Subject Matter Expert) expertise.Maintains and optimizes the Computerized Maintenance Management System (CMMS).Periodically review automation documents, preventive maintenance, and standard operating procedures to ensure compliance with GMP, environmental, and safety regulations.Develop corrective actions for automation anomalies and oversee investigations to prevent recurrence.Responsible for observing all Company, Health, Safety and Environmental guidelines.Execute with minimal guidance from Director of Systems and Controls Engineer, and lead department control system projects, schedules, and other necessary control system project tasks.Supports facility, utility, future manufacturing and filling/packaging related control systems along with capital projects.Review documentation, methods, equipment, and procedures to improve efficiencies.Domestic and overseas travel to equipment vendor facilities for FAT execution and other project assignments (Utilize life cycle methodologies and standards (GAMP5, S88, S95, 21 CFR Part 11) for the design, development, installation, qualification, and validation of existing and future control systems and building management control systems.Evaluate and select upgrades for legacy equipment to ensure proper part obsolescence initiatives are met.Other duties include, but not limited to, troubleshooting control and instrumentation systems to resolve discrepancies, install automated systems, configure automated systems, develop test strategies, execute test strategies, prepare protocols, execute protocols, prepare technical reports and write standard operating procedures.Develop control systems documentation, SOPs, along with system change controls, IQ, OQ, FAT/SAT/Commissioning, as required, to provide ongoing upgrades and new systems in support for cGMP Manufacturing and Utility control systems.Update and/or produce electrical drawings, control panel layouts, and other technical documentation in support of new or existing control systems.Required Skills & Experience:BS or Technical degree in engineering controls or a related field with 10-15 years of experience or MS/MBA with 7-10 years of experience or the equivalent combination of training and experience.In-depth knowledge of PLCs, SCADA, HMIs, Vision system, Robotics and Visual Basic.Proven ability to program PLCs, HMIs. Effective project management skills. PMP preferred.Subject matter expert knowledge of Allen Bradley and Siemens controllers. Graphical layout and design ability for HMI's a plus.Mastery knowledge of networks used in Manufacturing such as EtherNet, DeviceNet, Foundation Fieldbus, and others.5+ years experience operating, qualifying or developing batch processes, pure water systems, compressed air systems, HVAC systems, and Filling Units. (Lyophilizers, Freezers and Refrigerators a plus)Understanding and knowledge of ISA S88 and S95.Subject Matter Expert of validation principles, manufacturing processes, quality systems, engineering design fundamentals, regulatory expectations and industry trends.Sr. Level experience working in a regulated industry (Medical/Aerospace/Automotive), Knowledge of cGMPs, GAMP & 21 CFR part 11 validation requirement a plus.Mastery level in technical writing, verbal communication, interpersonal and problem-solving skills is required.Proven ability to work independently, lead a team of peers and manage assignments cross-functionally. Mastery level knowledge of historian data storage such as Wonderware InSQL, Factorytalk Historian, and query programs for real-time control systems a plus.Onsite work required, limited ability to be virtual/remote. Must be able to be "get dirty" and work hand and hand with mechanics, production engineers and interns. Position is not desk bound. Mastery level knowledge of Microsoft Word®, Excel®, Visio®, PowerPoint®, and AutoCAD®. Solidworks and G-code experience a plus.

This is what you will do: This position is responsible for leading research, design and execute scientific studies to enable the drug product (DP) process development, characterization, clinical manufacturing, and commercial validation of parenteral/injectable biologic products. Lead and support execution of stability studies, data processing, compiling and presentation of results supporting late-stage clinical activities as well as preparation for PPQ. The candidate will support the development of a variety of manufacturing unit operations including, but not limited to, drug substance (DS) freeze/thaw, compounding/mixing, sterile filtration, drug product filling of vials/syringes, visual inspection, and DS/DP transportation. A general understanding of protein chemistry and/or the ability to run biopharmaceutical assays in a laboratory is preferred. The role will lead manufacturing technology transfer activities in preparation for DS and DP PPQs, including but not limited to sending/receiving site process gap analysis, process FMEAs (failure mode and effects analysis), change control owner/leader, master batch record review, as well as leading at-scale/full scale process development studies, and authoring protocols, and reports. In addition, the candidate will support deviation investigations, change controls, and CAPAs utilizing electronic Quality system. The candidate will also provide clinical and commercial manufacturing site support including but not limited to periodic meetings, action item owner, and as necessary in-person on-site manufacturing support. This position is expected to interact regularly with cross-functional staff from Analytical Sciences & Quality Control, Drug Substance Process Development, Manufacturing Technical Services, Quality Assurance, and/or CMC Regulatory Affairs to support progress of the program and preparation of source documentation supporting BLA. You will be responsible for: Lead the design and execute studies for Alexion pharmaceuticals' clinical drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sites Lead progression of projects with cross functional stakeholders, as well as understand the cross functional implication of project activities and decisions with minimal supervision Prioritizing multiple assigned tasks and projects independently and as part of the team Contribute to the development of strategic project plans for molecules in clinical development Author SOPs, study protocols and technical reports with minimal supervision Participate in cross-functional development teams representing Injectable Drug Product Development Maintain knowledge of current trends in drug product manufacturing processes, manufacturing equipment and single use systems as well as associated global regulatory expectations and scientific principles and theories. Actively participate in department and team meetings including assuming ownership and delivering on assign action items Develop presentations for meetings with internal and external stakeholders with minimal supervision Mentor and train junior Associate Scientists and Engineers regarding drug product development You will need to have: Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or relevant Engineering/Life Sciences field with 7+ years of relevant experience or Master's degree with 6+ years of relevant work experience Self-driven initiative to find resolution for technical challenges Excellent interpersonal, collaborative and communication skills The duties of this role are generally conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours. We would prefer for you to have: Scientific and practical knowledge of protein biochemistry and/or drug product process development is preferred Previous experience in biotherapeutics development as well as relevant knowledge of cGMP and Quality expectations for PPQs and BLA is preferred Scientific understanding of protein stability, thermodynamics, mechanism of protein degradation, biotherapeutics drug formulation development and analytical tools used to test formulations is a plus High level proficiency in MS Office software including Word, Excel, Outlook, Visio, and PowerPoint In-person statement for 4 days in the office:When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

seeking a Project Engineer with a strong technical background to lead Engineering Integrated Project Teams (IPTs) in the Deep Space Portfolio in Space Systems. This position will take direction from the Engineering Leads in Lunar/Mars Transport Platforms, Lunar/Mars Orbital Platforms, or Lunar/Mars Surface Platforms. Deep Space hardware includes components for Active Thermal Control Systems (ATCS) and Environmental Control and Life Support Systems (ECLSS) for the Orion Spacecraft and for Gateway Lunar Space Station modules including the Habitation and Logistics Outpost (HALO). Pursuits include ATCS and ECLSS components for the Exploration Command Module (Mars Transit Vehicle), Gateway Airlock, Gateway International Habitat (I-HAB), Lunar Landers, and Pressurized Rover as well as Surface Power and Fuel Cells for Lunar Infrastructure.Responsibilities• Drive world class project management process using integrated scheduling, earned value management, and risk and opportunity management• Work collaboratively with other Engineering disciplines (Systems, Software, Mechanical, and Electrical), Programs, Production, Quality and Supply Chain to develop an integrated execution plan to satisfy customer requirements across applicable operating conditions• Facilitate project tasks with the various functional organizations to ensure alignment with overall project objectives.• Track team's integrated execution performance to plan• Analyze, identify, and address execution problems, recommend and implement resolutions to ensure the successful completion of project(s)• Forecast project revenues, monitor costs, and re-estimate project costs monthly to maximize project profitability and ensure business objectives are met• Maintain and present plans and progress reports relating to business aspects of the project(s) to track progress and ensure that established targets are met.• Ability to balance demands of multiple projects• Work autonomously with limited oversight from manager• Support root cause investigations and corrective actions for field returns and production issues• Develop bids based on customer proposal requests• Participate in continuous improvement efforts for project execution efficiency• Champion superior ethical and professional behavior in all situationsThe candidate will drive the execution of all engineering responsibilities on the program while meeting both internal and external customer expectations. Direct communication with customers will be required. This position requires strong interpersonal and communication skills (both verbal and written), technical experience, and the ability to work as cross-functional team member.