Electronic Engineer Salary in Connecticut, USA

This is what you will do:Alexion's Product Development and Clinical Supply (PDCS) organization is seeking an automation engineer to enable design and deployment of advanced laboratory and process automation systems for the Synthetic Process Development team, with emphasis on ensuring seamless data flow to enable modeling, AI/ML, data visualization, and data-rich experimental records. The Senior Automation Engineer, Synthetic Process Development, will leverage deep data engineering and laboratory automation expertise and will focus on the architecture, design, control, and data management of robotics and automated systems that will drive efficiency, inform data-driven decisions, and enable the design and development of pharmaceutical manufacturing processes. You will collaborate extensively with Alexion scientists and engineers as well as external partners to provide data management and operational solutions for laboratory and process automation.You will be responsible for:Designing, deploying, and sustaining software and data management solutions to enable innovative laboratory automaton systems, as well as highly flexible and reconfigurable automated miniaturized manufacturing systems.Leveraging expertise in multiple programming languages, database management systems, and cloud technology to enable advanced laboratory and process automation for pharmaceutical research and development.Acting as the Synthetic Process Developoment team's main point of contact with Alexion / AstraZeneca IT partners, and clearly translating scientific business requirements into actionable IT and data management strategies.Driving innovation and leading collaborations with strategic partners.Acting as a thought leader in data engineering, robotics, and automated process control, with demonstrated mastery of multiple automation platforms and ability to rapidly gain proficiency in additional platforms.Building a comprehensive understanding of scientific workflows and key data flows within the Synthetic Process Development team, and applying this understanding to create a strategic vision for the development of future laboratory and process automation systems, and associated innovations in data management strategies.Keeping up-to-date with the latest advancements through publications, participation in precompetitive consortia, via knowledge exchange with strategic business partners, and where possible, via conference attendance.You will need to have:Degree in software engineering, computer science, or related scientific field (chemical engineering, robotics, etc.) with relevant hands on experience in data engineering, robotics, and laboratory automation (PhD or Postdoc: 0-5 years experience, MS: 5+ years experience, BSc: 10+ years experience).Expertise in multiple programming languages (Python, C#, etc.), database management (SQL, NoSQL, etc.), and cloud technology (AWS, serverless design pattern, etc.).Expertise in creating, modifying and troubleshooting scripts for laboratory robotics and process automation, and managing seamless data flow.Demonstrated ability to work independently in a fast-paced team-centered environment, and rapidly learn new skills.Excellent verbal and written communication skills.Experience in design and deployment of integrated automated platforms incorporating components from multiple vendors, with emphasis on integrated data management strategies.Ability to plan and execute complex technical projects, and remotely manage timelines for development activities at external strategic business partners.Up to 15% travel, with ability to work independently from remote locations.The duties of this role may require periodic work in a laboratory or manufacturing environment. As is typical of such roles, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.We would prefer for you to have:Experience in automated chemical synthesis, analysis, and purification.Understanding of the overall drug development and commercialization process, from discovery through product launch and lifecycle management.Prior experience in chemometrics, including use of multivariate data analysis, in situ reaction monitoring, reaction profiling, and development of first-principles process chemistry models.Working knowledge of flow chemistry and continuous processing.In-person statement for 4 days in the office:When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

This is what you will do:This position will partner on business strategy and driving process and technology across Data Sciences/Bioinformatics/Genomics, Internal Research, External Research, Bioanalytical Development, Translational Medicine, Pre-Clinical Research, and Discovery Sciences. The role will require the ability to match IT strategy to Research priorities and then translate this strategy into execution with a "hands-on" approach to delivering IT solutions. You will work with IT and business partners to build an outstanding architecture framework and strategy, implementation roadmaps, and governance, to support the constantly evolving needs in the BioPharma industry. The resulting strategy will be based on industry guidelines and Alexion standards, while periodically evolving in alignment with future business needs and capabilities. You will apply the strategic framework to establish a target-state architecture that will guide the design, development, and delivery of key IT solutions in supporting the business strategy/needs!You must have excellent communication and customer service skills and must be prepared to regularly use these skills in presentations to colleagues. Constructive communication will be encouraged down to the most junior staff members as well as up the leadership ladder. In all endeavors, they must maintain a professional level of preparation and performance.In addition, you must stay abreast of new technologies and be willing to present and/or train fellow team members on the technologies. You should have a demeanor of continuous improvement and strive to make one thing better every day.You must also manage ambiguity and complexity, optimize work processes and drive engagement, get results, and overall drive the implementation and adoption of business IT Quality and Laboratory systems to meet the Business requirements. Alexion process demands that operational streamlining and efficiency is driven by a simple, compliant, and suitable business process that meets the strategic goals of accommodating growth and compliance.You will be responsible for:Designs solution blueprints for projects or solutions that address business/application/data/infrastructure requirements.Works with Business Analysis and Solution Architecture functions and supports functional & technical requirements management, including driving software selection processes.Ensures that solution architectures and designs are appropriately robust and address business, application, information and infrastructure architectural requirements. Accountable for designing comprehensive solutions that meet business requirements and are aligned to AstraZeneca's Enterprise Architecture, in support of a given portfolio. The Solution Engineer will partner with project managers, business analysts, and solution architects to create solutions that are aligned to AstraZeneca architecture standards and principles, leverage common solutions and services, and meet the financial targets (cost and benefits). Within the solution development lifecycle the role will be accountable for solution evaluation and selection, buy vs. build decisions, and early-phase project estimates which contribute to the business case.Provides technical & IT expertise support to project teams and conducts AZ architectural reviews throughout project lifecycle.Ensures compliance with existing EA guidelines and standards (e.g. AZ Architecture Engagement Process (ISPMM) and EA Software Standards)Contributes to project and service teams in the development, implementation and maintenance of standard architectural components.Works with third party suppliers as required and contributes to the creation of local or functional design documents. Works with third party suppliers to verify technical development and delivery are in alignment with the Architecture Roadmap, Blueprint and Information Services Strategy.Documents all architecture analysis and design workDevelops solid understanding and expertise in at least one architecture domainContributes to the development of the Architecture Capability within Information Services, by documenting and sharing knowledge and standard methodologies with peer Engineers. You will need to have:Degree in an IT/ or Business-related field.9+ years progressive experience in Research / Quality / Laboratory systems within a regulated enterprise environment.Strong multi-functional knowledge across Research Labs & associated Technologies & Processes.Laboratory Network Infrastructure understanding.Computer Systems Validation, GAMP5 experience and familiarity with both regulatory (GxP) and corporate compliance domains.Project Management experience - 3+ years.Systems selection process and RFP.IT Tools and processes as it relates to ITIL/ISPE.Experience developing innovative solutions, blueprints, and standards for solution design.3+ years Relationship management.The duties of this role are generally conducted in an office environment. As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.We would prefer for you to have:Detail-oriented and ability to work independently and collaboratively in a deadline-driven environment.Prior experience integrating systems to support lab data capture, analysis, scientific knowledge management, and enabling external teamwork.Experience with Research laboratory systems and processes (ELN, SDMS, bioinformatics platforms, lab automation, protein/molecular sciences & engineering, drug screening, biologics research, preclinical research), analytical chemistry, fermentation, and process management.Excellent communication skills and ability to interact with colleagues at all levels.Strong analytical, problem solving and critical thinking skills.Strategic mentality and experience with supporting a Research Operations environment.Ability to act decisively in an uncertain environment.Expectation of working in the office 3 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

Triumph GroupBusiness Overview Location: West Hartford, CT, US, 06110-1328Business Unit: Systems and SupportFunction: Engineering About UsTriumph Group designs, engineers, manufactures, repairs, and overhauls a broad portfolio of aviation and industrial components, accessories, subassemblies, systems, and aircraft structures. We partner with original equipment manufacturers (OEMs) and operators of commercial, regional, business, and military aircraft worldwide, to provide products and services that solve their hardest problems. So, whatever the part, component or complexity of assembly, Triumph is committed to quality, service and meeting the specialized needs of each customer. Triumph participates at all levels of the aerospace supply chain – from single components to complex systems, to aerospace structures and their contents. We provide solutions for the entire product life cycle of an aircraft – from raw material to aftermarket service. Our unique ability to integrate a broad range of products and capabilities is our competitive advantage. Based in West Hartford CT, Triumph Systems, Electronics and Controls is a leading independent aerospace system supplier for the commercial and military helicopter and business jet markets and employs approximately 500 employees. The Company's key products and services include electronic engine controls, fuel metering units, main fuel pumps and environmental control systems for both the OE and aftermarket/spares end markets. We are rapidly growing and looking for people who feel rewarded by innovation, career growth, and making an impact and while working with state-of-the-art equipment on cutting-edge projects. If you're ready to be challenged, inspired, and supported as you pursue your professional best, we hope you'll explore a future with TRIUMPH.PositionWe have an exciting opportunity for an Obsolescence, Electronic Components & Logistics Engineer to join our West Hartford, CT team. The ideal candidate for this position should have a good technical background in Electronic Components, able to perform datasheet review and part comparison.Responsibilities•Familiar with a Product Data Management (PDM) or Product Lifecycle Management (PLM) tools,•Comfortable communicating with internal customers and team-members•Self-motivated and possess good interpersonal/team skills. •Experience with uploading/downloading, parsing, and analyzing electronic files (e.g. Excel format)•Communicate with PCB contract manufacturers, interface with Supply Chain, Purchasing, Project and Electronics Design; generate ‘Where Used' reports, and accurately track inventory and life-cycle data. Desired Knowledge, Skills & Abilities: •Technical oDatasheet Review (component parametrics, AEC-Qualifications, GiDEP, PCNs) oAnalysis Tools (Excel) oInventory Management Tools oDocumentation Tools (MS Word/PowerPoint, Visio, Adobe, Nuance)•Non-Technical oSchedule Tracking (MS Project) oInternet (SharePoint, Intranet)Qualifications•Minimum of a Bachelors' Degree in Electrical Engineering. Associates Degree may be considered•More than 2-years of relevant Electronics Engineering, Component Selection or Avionics Design experience. •Familiarity with Silicon Expert, IHS, CAPSEXPERT, DIGIKEY, FINDCHIPS, OCTOPART or other similar EDA search tools•Familiarity with Omnify Empower PLM tools preferred•Excellent written and verbal skills.•Able to work independently or across teams.Benefits•Comprehensive medical, dental and vision coverage with plan options that provide flexibility and choice (including telehealth options)•Healthcare spending accounts•Paid parental leave•Paid/flexible time off in addition to paid company holidays•401(k) with company match•Employee Stock Purchase Plan•Disability and life insurance•Incentives and performance-based rewards•Exciting growth and development opportunities empowered by our TRIUMPH Transformation and an entrepreneurial environment that encourages innovation and creativityVision and MissionOur Vision:As one team, we enable the safety and prosperity of the world. Our Mission:We partner with our Customers to TRIUMPH over their hardest aerospace, defense, and industrial challenges to deliver value to our stakeholders. Our Values:1.Integrity – Do the right thing for our stakeholders. We value safety, diversity, and respect.2.Teamwork – Win as One team-one company. Solicit help and assist others.3.Continuous Improvement – Pursue zero defect quality. Attack problems and relentlessly raise the bar.4.Innovation – Passion for growing the business. Lead through ingenuity and entrepreneurship.5.Act with Velocity – Partner, anticipate and communicate. Proactively solve problems.Physical Demands The work environment characteristics and physical demands described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is regularly required to sit, talk, or hear. The employee frequently is required to stand, walk, and use hands to finger, handle, or feel objects, tools, or controls. The employee is occasionally required to reach with hands and arms: stoop, kneel, crouch, or crawl. The employee must occasionally lift and/or move up to 30 pounds. EHSEmployees are responsible for the Health, Safety, and Welfare of themselves, the environment, and other people. All employees must comply with EHS policy training and instructions, help to maintain a safe and clean working environment, and use any Personal Protective Equipment (PPE) provided by the Company. Employees must report any accidents, incidents, and near misses to management. Additionally, employees are expected to notify management of any dangerous or potentially dangerous situations or practices.Code of ConductTo perform the job successfully, an individual should demonstrate the TRIUMPH behaviors captured within our core values: Integrity, Teamwork, Continuous Improvement, Innovation, and Act with Velocity. Detailed definitions are below and performance metrics for each behavior can be found on our intranet and is embedded within our Performance Management processes. All employees are expected to represent the values and maintain the standards contained in TRIUMPH's Code of Conduct. Pursuant to International Traffic Arms Regulations (ITAR) and the Export Administration Regulations (EAR), applicants for SELECT positions will be required to provide proof of U.S. Citizenship, U.S. Permanent Residence, or U.S. Immigration Status in order to meet the minimum qualifications for those select positions. All inquiries related to citizenship are asked solely to comply with ITAR and EAR export licensing requirements. Legally authorized to work in the United States without company sponsorship. Triumph Group and all its divisions and subsidiaries are Equal Opportunity/Affirmative Action Employers. Triumph Group provides reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Assistance Act of 1974 and Title I of the Americans with Disabilities Act of 1990. Applicants who need accommodation in the job application process should [email protected] request assistance. Include the title of the position and location in the subject line of your email so we may direct your email to the appropriate person. Please note that only those inquiries concerning a request for reasonable accommodation will be responded to."An Equal Opportunity Employer - Minorities/Females/Disabled/Veterans" We are an Equal Opportunity Employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, or any other characteristic protected by law. Pursuant to International Traffic Arms Regulations (ITAR) and the Export Administration Regulations (EAR), applicants for SELECT positions will be required to provide proof of U.S. Citizenship, U.S. Permanent Residence, or U.S. Immigration Status in order to meet the minimum qualifications for those select positions. All inquiries related to citizenship are asked solely to comply with ITAR and EAR export licensing requirements.The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information. 41 CFR 60-1.35(c).PI239960792

This is what you will do:This position will serve the role of Engineer II for device development / human factors engineering within the Alexion Device Development organization. The role will support the human factors workstreams for pipeline products as well as lifecycle management. This role will interact with multiple functional teams including Device Development, Clinical, Commercial/Marketing, Quality, and Regulatory, clinical development through registration and commercial product support. You will be responsible for:Lead and support activities under the human factors and usability engineering process for combination product design and development from feasibility, clinical development through registration and post-market.Support core teams to develop and support the strategy for human factors/ usability engineering activities from formative studies to final HF validation for combination products.Support design validation activities including summative human factors study (i.e. human factors validation) from protocol development, study execution, and reporting.Provide input for user need identification and user interface specifications development.Author use-related risk management activities such as known use problem analysis, hazard analysis, and use-related risks analysisDraw learnings from competitive analysis, market sensing, complaint handling to inform new product design (inclusive of device, labeling and secondary packaging) Interface with human factors firms (vendors) and manage their activities for a formative or summative human factors study.Communicate effectively, both verbally and in writing, internally across departments and with external suppliers.Ensure all human factors engineering activities as required and comply with the Company's quality assurance requirements as well as applicable regulatory requirements.Support feasibility activity of device assessment (e.g., testing, fixturing, protocol, report).You will need to have:Experience in human factors engineering and exposure to design and development of medical device and combination products.Awareness of design control activities .Ability to manage external human factors firms (vendors).Strong communication and collaboration skills; ability to connect with all levels of the organization. Proficient in writing internal reports, project summaries, and internal/external presentations.Knowledge of human factor/usability engineering, safety, performance and regulatory compliance requirements of medical device and combination products (e.g. IEC 62366, FDA HF guidances, EU Regulation 2017/745 (MDR)).[For office-based positions:] As is typical of an office-based role, employees must be able, with or without an accommodation to: use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours. We would prefer for you to have:Bachelor's or Master's degree in Engineering (Biomedical, Chemical, Mechanical, Electrical Engineering or Human Factors) plus 0-3 year experience in medical device Human Factors development. Experience with injection based combination product development and risk management preferred. Experience with graphics design a plus.AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

This is what you will do: This position will lead research, design and implement scientific studies to enable the drug product (DP) process development, characterization, clinical manufacturing, and commercial validation of parenteral/injectable biologic products. Lead and support execution of stability studies, data processing, compiling and presentation of results supporting late-stage clinical activities as well as preparation for PPQ. Develop a variety of manufacturing unit operations including, drug substance (DS) freeze/thaw, compounding/mixing, sterile filtration, drug product filling of vials/syringes, visual inspection, and DS/DP transportation. A general understanding of protein chemistry and/or the ability to run biopharmaceutical assays in a laboratory is preferred.The role will lead manufacturing technology transfer activities in preparation for DS and DP PPQs, sending/receiving site process gap analysis, process FMEAs (failure mode and effects analysis), change control owner/leader, master batch record review, as well as leading at-scale/full scale process development studies, and authoring protocols, and reports. In addition, will support deviation investigations, change controls, and CAPAs using electronic Quality system. The candidate will also provide clinical and commercial manufacturing site support including but not limited to periodic meetings, action item owner, and in-person on-site manufacturing support. Interact regularly with multi-functional staff from Analytical Sciences & Quality Control, Drug Substance Process Development, Manufacturing Technical Services, Quality Assurance, and/or CMC Regulatory Affairs to support progress of the program and preparation of source documentation supporting BLA.You will be responsible for: Own the design and implement studies for Alexion pharmaceuticals' clinical drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sitesLead progression of projects with multi-functional collaborators, as well as understand the implications of project activities and decisions with minimal directionPrioritizing multiple tasks and projects independently and as part of the teamAuthor SOPs, study protocols and technical reportsParticipate in multi-functional development teams representing Injectable Drug Product DevelopmentMaintain knowledge of current trends in drug product manufacturing processes, manufacturing equipment and single use systems as well as associated global regulatory expectations and scientific principles and theories. Train other peers as assigned in areas of expertiseActively participate in department and team meetings including assuming ownership and delivering on assign action itemsDevelop presentations for meetings with internal and external partnersYou will need to have:Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or relevant Engineering/Life Sciences field with 4+ years of relevant experience or Master's degree with 3+ years of relevant work experienceDedicated initiative to find resolution for technical challengesExcellent interpersonal, collaborative and communication skillsThe duties of this role are conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.We would prefer for you to have:Scientific and practical knowledge of protein biochemistry and/or drug product process developmentPrevious experience in bio-therapeutics development as well as relevant knowledge of cGMP and Quality expectations for PPQs and BLAScientific understanding of protein stability, thermodynamics, mechanism of protein degradation, bio-therapeutics drug formulation development and analytical tools used to test formulations is a plusHigh level proficiency in MS Office software including Word, Excel, Outlook, Visio, and PowerPointExpectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world!AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

This is what you will do: This position will lead research, design and implement scientific studies to enable the drug product (DP) process development, characterization, clinical manufacturing, and commercial validation of parenteral/injectable biologic products. Lead and support execution of stability studies, data processing, compiling and presentation of results supporting late-stage clinical activities as well as preparation for PPQ. Develop a variety of manufacturing unit operations including, drug substance (DS) freeze/thaw, compounding/mixing, sterile filtration, drug product filling of vials/syringes, visual inspection, and DS/DP transportation. A general understanding of protein chemistry and/or the ability to run biopharmaceutical assays in a laboratory is preferred.The role will lead manufacturing technology transfer activities in preparation for DS and DP PPQs, sending/receiving site process gap analysis, process FMEAs (failure mode and effects analysis), change control owner/leader, master batch record review, as well as leading at-scale/full scale process development studies, and authoring protocols, and reports. In addition, will support deviation investigations, change controls, and CAPAs using electronic Quality system. The candidate will also provide clinical and commercial manufacturing site support including but not limited to periodic meetings, action item owner, and in-person on-site manufacturing support. Interact regularly with multi-functional staff from Analytical Sciences & Quality Control, Drug Substance Process Development, Manufacturing Technical Services, Quality Assurance, and/or CMC Regulatory Affairs to support progress of the program and preparation of source documentation supporting BLA.You will be responsible for: Own the design and implement studies for Alexion pharmaceuticals' clinical drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sitesLead progression of projects with multi-functional collaborators, as well as understand the implications of project activities and decisions with minimal directionPrioritizing multiple tasks and projects independently and as part of the teamAuthor SOPs, study protocols and technical reportsParticipate in multi-functional development teams representing Injectable Drug Product DevelopmentMaintain knowledge of current trends in drug product manufacturing processes, manufacturing equipment and single use systems as well as associated global regulatory expectations and scientific principles and theories. Train other peers as assigned in areas of expertiseActively participate in department and team meetings including assuming ownership and delivering on assign action itemsDevelop presentations for meetings with internal and external partnersYou will need to have:Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or relevant Engineering/Life Sciences field with 4+ years of relevant experience or Master's degree with 3+ years of relevant work experienceDedicated initiative to find resolution for technical challengesExcellent interpersonal, collaborative and communication skillsThe duties of this role are conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.We would prefer for you to have:Scientific and practical knowledge of protein biochemistry and/or drug product process developmentPrevious experience in bio-therapeutics development as well as relevant knowledge of cGMP and Quality expectations for PPQs and BLAScientific understanding of protein stability, thermodynamics, mechanism of protein degradation, bio-therapeutics drug formulation development and analytical tools used to test formulations is a plusHigh level proficiency in MS Office software including Word, Excel, Outlook, Visio, and PowerPointExpectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world!Date Posted26-Apr-2024Closing Date30-Jul-2024Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact [email protected]. Alexion participates in E-Verify.AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

Triumph GroupBusiness OverviewLocation: West Hartford, CT, US, 06110-1328Business Unit: Systems and SupportFunction: Engineering About UsTriumph Group designs, engineers, manufactures, repairs, and overhauls a broad portfolio of aviation and industrial components, accessories, subassemblies, systems, and aircraft structures. We partner with original equipment manufacturers (OEMs) and operators of commercial, regional, business, and military aircraft worldwide, to provide products and services that solve their hardest problems. So, whatever the part, component or complexity of assembly, Triumph is committed to quality, service and meeting the specialized needs of each customer. Triumph participates at all levels of the aerospace supply chain – from single components to complex systems, to aerospace structures and their contents. We provide solutions for the entire product life cycle of an aircraft – from raw material to aftermarket service. Our unique ability to integrate a broad range of products and capabilities is our competitive advantage. Based in West Hartford CT, Triumph Systems, Electronics and Controls is a leading independent aerospace system supplier for the commercial and military helicopter and business jet markets and employs approximately 500 employees. The Company's key products and services include electronic engine controls, fuel metering units, main fuel pumps and environmental control systems for both the OE and aftermarket/spares end markets. We are rapidly growing and looking for people who feel rewarded by innovation, career growth, and making an impact and while working with state-of-the-art equipment on cutting-edge projects. If you're ready to be challenged, inspired, and supported as you pursue your professional best, we hope you'll explore a future with TRIUMPH.PositionWe have an exciting opportunity for a Power Electronics Design Engineer to join our West Hartford, CT team. Our Power Electronics Design Engineers develop unique solutions that perform actuator controls, motor controls, environmental controls, electro-mechanical sensor interfacing, fuel/fluid regulation, digital communication, and input power conditioning. Additionally, these individuals possess a broad knowledge across many areas of Avionic Systems ranging from EMI, EMC and Lightning compliance, Environmental, Test and Systems Architecture, to name a few. Responsibilities•Collaborate with other cross-functional team leads and engineers to plan and execute projects, ensure that teams have appropriate product and technical specifications, direction, and resources to deliver products effectively by establishing realistic estimates for timelines while ensuring that projects remain on target to meet deadlines.•Perform requirements development, allocation, and compliance assessment•Generate block diagrams for various design concepts, system and circuit topologies•Perform preliminary and detailed analyses or simulations•Ensure overall compliance to TECS internal processes (e.g. NPI, Standard Work, Design Reviews)•Meet or exceed DFx, Design-To-Cost and Design-To-Weight targets•Support internal and external customer meetings•Perform Design Assurance and/or Qualification Testing•Support the transition of a program from development to productionQualificationsBackground•MSEE, with coursework in power electronics, motors and motor drive technology•Greater than 4 - years of relevant Aerospace-Avionics design experience preferred. •Greater than 2 - years of direct experience in Power Electronics and Control System Design •Excellent written and verbal skills.•Excellent Troubleshooting and Problem-Solving Skills. Experience•High power AC (3-PH, variable frequency input, 120/208/440VAC) design and development•High power DC input motor drive (1 - 100 kW) design and development•High power Boost Converter design and development•High voltage DC Inverter design and development•Power System Design - Power System Noise, System Simulation and Modeling, Solid State Transmitters, Tube Transmitters, High Voltage Design, Power Sources, Generators •Power Conversion - AC/DC, DC/DC and DC/AC, Linear and Switching Supplies, Power Factor Correction (PFC), Zero Voltage Switching (ZVS), Resonant Circuits, Synchronization, Noise Controls •Power Distribution - Ground, Air, and Space, Power Generation, Line Voltage, High Current, Low Voltage, Micro-Power, DC, AC, Multi-Phase Power Control, Fault Reporting, Isolation, Protection Circuits, Redundant Systems •Power Sub-System Design - Filters, Harmonic Control, EMI, Circuit Simulation, Magnetics, Protective Relay Systems, Short Circuit and Stress Analyses •Control Systems - Servo Control Systems, Motor/Power/Process Control, Digital Feedback Systems, Command Generation, Inertial Stabilization•Texas Instruments TMS320F28335 (motor controller) DSP hardware and C software design and development for variable speed drives incorporating vectored sensor and sensor less motor drive algorithms•Rectifier and Inverter designs using discrete and COTS IGBT technology•Full life cycle engineering support of Airborne Electronic Hardware (AEH) in accordance with RTCA DO-254. In addition, the candidate should have experience with power electronics modeling and simulation tools (PLEX, SABER, System Vision), be capable of safely working with high power electronics, power sources and test instrumentation, experience with various motor technologies (BLDC and PMAC), and experience and knowledge of high power rotating machinery (compressors, fans and pumps). Knowledge and experience with environmental control systems is a plus. Desired Skills Technical•Simulation Tools (LTSpice, SABER, PLEX, System Vision, MathWorks/Simulink)•Analysis Tools (Mathcad, MS Excel, Minitab, Matlab)•CAD Tools (Mentor Graphics suite: PADS, Hyperlynx, DxDesigner)•Documentation Tools (MS Word/PowerPoint, Visio, Adobe, Nuance)•Requirements & Configuration Management (Teamcenter, DOORs)•H/W Programming Languages (Labview, Visual Basic, eTPU micro-code)•FPGA/PLD devices (from Actel, Xilinx, Altera) Non-Technical•Schedule Tracking (MS Project)•Internet (SharePoint, Intranet)•Knowledge of Test and Manufacturing processes in an aerospace electronics environment.•Knowledge of DO-160 and MIL-STD 461 requirements for aerospace electronics.Benefits •Comprehensive medical, dental and vision coverage with plan options that provide flexibility and choice (including telehealth options)•Healthcare spending accounts•Paid parental leave•Paid/flexible time off in addition to paid company holidays•401(k) with company match•Employee Stock Purchase Plan•Disability and life insurance•Incentives and performance-based rewards•Exciting growth and development opportunities empowered by our TRIUMPH Transformation and an entrepreneurial environment that encourages innovation and creativityVision and MissionOur Vision:As one team, we enable the safety and prosperity of the world. Our Mission:We partner with our Customers to TRIUMPH over their hardest aerospace, defense, and industrial challenges to deliver value to our stakeholders. Our Values:1.Integrity – Do the right thing for our stakeholders. We value safety, diversity, and respect.2.Teamwork – Win as One team-one company. Solicit help and assist others.3.Continuous Improvement – Pursue zero defect quality. Attack problems and relentlessly raise the bar.4.Innovation – Passion for growing the business. Lead through ingenuity and entrepreneurship.5.Act with Velocity – Partner, anticipate and communicate. Proactively solve problems.Physical DemandsThe work environment characteristics and physical demands described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. While performing the duties of this job, the employee is regularly required to sit, talk, or hear. The employee frequently is required to stand, walk, and use hands to finger, handle, or feel objects, tools, or controls. The employee is occasionally required to reach with hands and arms: stoop, kneel, crouch, or crawl. The employee must occasionally lift and/or move up to 30 pounds.EHSEmployees are responsible for the Health, Safety, and Welfare of themselves, the environment, and other people. All employees must comply with EHS policy training and instructions, help to maintain a safe and clean working environment, and use any Personal Protective Equipment (PPE) provided by the Company. Employees must report any accidents, incidents, and near misses to management. Additionally, employees are expected to notify management of any dangerous or potentially dangerous situations or practices. Code of Conduct To perform the job successfully, an individual should demonstrate the TRIUMPH behaviors captured within our core values: Integrity, Teamwork, Continuous Improvement, Innovation, and Act with Velocity. Detailed definitions are below and performance metrics for each behavior can be found on our intranet and is embedded within our Performance Management processes. All employees are expected to represent the values and maintain the standards contained in TRIUMPH's Code of Conduct. Pursuant to International Traffic Arms Regulations (ITAR) and the Export Administration Regulations (EAR), applicants for SELECT positions will be required to provide proof of U.S. Citizenship, U.S. Permanent Residence, or U.S. Immigration Status in order to meet the minimum qualifications for those select positions. All inquiries related to citizenship are asked solely to comply with ITAR and EAR export licensing requirements. Legally authorized to work in the United States without company sponsorship. Triumph Group and all its divisions and subsidiaries are Equal Opportunity/Affirmative Action Employers. Triumph Group provides reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Assistance Act of 1974 and Title I of the Americans with Disabilities Act of 1990. Applicants who need accommodation in the job application process should [email protected] request assistance. Include the title of the position and location in the subject line of your email so we may direct your email to the appropriate person. Please note that only those inquiries concerning a request for reasonable accommodation will be responded to."An Equal Opportunity Employer - Minorities/Females/Disabled/Veterans" We are an Equal Opportunity Employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status, or any other characteristic protected by law. Pursuant to International Traffic Arms Regulations (ITAR) and the Export Administration Regulations (EAR), applicants for SELECT positions will be required to provide proof of U.S. Citizenship, U.S. Permanent Residence, or U.S. Immigration Status in order to meet the minimum qualifications for those select positions. All inquiries related to citizenship are asked solely to comply with ITAR and EAR export licensing requirements.The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor's legal duty to furnish information. 41 CFR 60-1.35(c).PI240386509

This is what you will do: This position is responsible for leading research, design and execute scientific studies to enable the drug product (DP) process development, characterization, clinical manufacturing, and commercial validation of parenteral/injectable biologic products. Lead and support execution of stability studies, data processing, compiling and presentation of results supporting late-stage clinical activities as well as preparation for PPQ. The candidate will support the development of a variety of manufacturing unit operations including, but not limited to, drug substance (DS) freeze/thaw, compounding/mixing, sterile filtration, drug product filling of vials/syringes, visual inspection, and DS/DP transportation. A general understanding of protein chemistry and/or the ability to run biopharmaceutical assays in a laboratory is preferred. The role will lead manufacturing technology transfer activities in preparation for DS and DP PPQs, including but not limited to sending/receiving site process gap analysis, process FMEAs (failure mode and effects analysis), change control owner/leader, master batch record review, as well as leading at-scale/full scale process development studies, and authoring protocols, and reports. In addition, the candidate will support deviation investigations, change controls, and CAPAs utilizing electronic Quality system. The candidate will also provide clinical and commercial manufacturing site support including but not limited to periodic meetings, action item owner, and as necessary in-person on-site manufacturing support. This position is expected to interact regularly with cross-functional staff from Analytical Sciences & Quality Control, Drug Substance Process Development, Manufacturing Technical Services, Quality Assurance, and/or CMC Regulatory Affairs to support progress of the program and preparation of source documentation supporting BLA. You will be responsible for: Lead the design and execute studies for Alexion pharmaceuticals' clinical drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sites Lead progression of projects with cross functional stakeholders, as well as understand the cross functional implication of project activities and decisions with minimal supervision Prioritizing multiple assigned tasks and projects independently and as part of the team Contribute to the development of strategic project plans for molecules in clinical development Author SOPs, study protocols and technical reports with minimal supervision Participate in cross-functional development teams representing Injectable Drug Product Development Maintain knowledge of current trends in drug product manufacturing processes, manufacturing equipment and single use systems as well as associated global regulatory expectations and scientific principles and theories. Actively participate in department and team meetings including assuming ownership and delivering on assign action items Develop presentations for meetings with internal and external stakeholders with minimal supervision Mentor and train junior Associate Scientists and Engineers regarding drug product development You will need to have: Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or relevant Engineering/Life Sciences field with 7+ years of relevant experience or Master's degree with 6+ years of relevant work experience Self-driven initiative to find resolution for technical challenges Excellent interpersonal, collaborative and communication skills The duties of this role are generally conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours. We would prefer for you to have: Scientific and practical knowledge of protein biochemistry and/or drug product process development is preferred Previous experience in biotherapeutics development as well as relevant knowledge of cGMP and Quality expectations for PPQs and BLA is preferred Scientific understanding of protein stability, thermodynamics, mechanism of protein degradation, biotherapeutics drug formulation development and analytical tools used to test formulations is a plus High level proficiency in MS Office software including Word, Excel, Outlook, Visio, and PowerPoint In-person statement for 4 days in the office:When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

This is what you will do:The Engineer II will design and implement experiments to develop injectable drug product formulations and process characterization studies, including analyzing samples and authoring technical reports. Work on an impactful dynamic team and routinely collaborate to innovate with other members of Injectable Drug Product Development as well as other groups in Product Development and Clinical Supply!You will be responsible for:Execution of formulation screening and stability studies for injectable drug products including proteins, siRNAs, peptides.Drive supporting analytical methods and analysis for samplesSupporting process development and tech transfer of GMP fill finish processes to internal and external manufacturing organizations.Defining drug product processes, scale up studies, transferring information between development and manufacturing sites, as well as preparation of required tech transfer document.Knowledge of cGMP and quality guidelines is required.Authoring internal technical reports on the implemented studiesAssisting in preparation of external regulatory submissions for the Alexion product candidates.Participate in department meetings and other technical and team building activities.You will need to have:Firsthand experience on developing phase appropriate drug product formulations and fill finish processes.Basic principles of protein chemistry and stability, and biologic therapeutic degradation mechanisms.Proven success working with cross functional partners.Firsthand experience with liquid chromatography methods (e.g., SEC, IEX, HIC) and capillary methods (e.g. iCE, LabChip GXII Touch).Strong knowledge of analytical software (e.g. Empower, JMP).Experience with electronic record keeping software, like ELN.Ability to work in a collaborative setting and adhere to timelines is essential.The duties of this role are conducted in an lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious, and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.We would prefer for you to have:BS or MS degree in Biochemistry, Chemistry, Chemical Engineering or related field from an accredited university with 1+ years of experience for MS or 2+ years of experience with BS.Excellent interpersonal and collaboration skills!Understanding of the biotechnology products life cycle and factors impacting product stability.Expectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

This is what you will do:The Engineer I will join and engaging Injectable Drug Product Development group to support the development of Alexion's biotherapeutic candidates. Design and implement experiments to develop injectable drug product formulations and process characterization studies, including analyzing samples and authoring technical reports. Work in a dynamic team environment and routinely collaborate with other members of Injectable Drug Product Development as well as other groups in Product Development and Clinical Supply.You will be responsible for:Execution of formulation screening and stability studies for injectable drug products including proteins, siRNAs, peptides.Supporting analytical methods and analysis for samplesSupporting process development and tech transfer of GMP fill finish processes to internal and external manufacturing organizations.Writing internal technical reports on the implemented studiesAssisting in preparation of external regulatory submissions for the Alexion product candidates.Participate in department meetings and other technical and team building activities.You will need to have:With some supervision, design and drive phase appropriate formulations and fill finish processes.proficient basic principles of protein chemistry and stability, and biologic therapeutic degradation mechanisms.Ability to work in a collaborative setting and adhere to timelines.Successful and effective collaborating in a multi-functional setting.Hands-on experience with liquid chromatography methods (e.g., SEC, IEX, HIC) and capillary methods (e.g. iCE, LabChip GXII Touch).Analytical software (e.g. Empower, JMP).Experience with electronic record keeping software, like ELN.Ability to work in a collaborative setting and adhere to timelines is essential.We would prefer for you to have:BS or MS degree in Biochemistry, Chemistry, Chemical Engineering or related field from an accredited university with 0-2 years of experience.Excellent interpersonal and relationship development!Understanding of the biotechnology products life cycle and factors impacting product stability.Basic knowledge of cGMP and Quality guidelines.Expectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world!AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.