Medical Laboratory Scientist Salary in Cambridge, MA

Biologics - Upstream Cell Line Development Employee Responsibilities include, but are not limited to: Support the cell line development (CLD) team through participation in transfection, stable selection, cloning, expansion and characterization of mammalian cell lines for clinical and commercial production Perform laboratory experiments using a variety of CLD and cell culture technologies including single cell cloning/clone picking, cell imaging, liquid handling automation and Octet/ELISA-based recombinant protein quantification Support molecular characterization of the lead clonal cell lines for CLD programs including but not limited to mRNA analysis and gene copy number determination Works with departmental and/or cross functional peers to execute on assignments, under limited supervision. Prepares experimental protocols. Contributes significantly to project work which may include multiple projects within functional area. Interprets data independently, and contributes to technical reports Identifies technical issues, and implements solutions under supervision Contributes to the design of new applications/experiments/unit operations in consultation with supervisor. Coordinates within department as well as cross functionally with peers on projects. The Ideal Candidate would possess: Experience in CLD technologies including culture of mammalian cells, single-cell cloning (sorting/clone picking), clonality assessment, and clone screening highly desirable Experience in molecular biology methods including subcloning, RT-qPCR/ddPCR and Octet/ELISA-based recombinant protein quantification is desirable Experience with FACS, automation or Next-Gen Sequencing will be a plus. Familiar with general laboratory procedures and aseptic technique. Able to troubleshoot critical issues or problems and resolve routine issues using appropriate information. Ability to work within department groups/team. Exercises good time management skills Proficiency in use of applicable lab equipment and operations; experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic) Expresses one's self clearly and concisely within function; documents issues and/or concerns concisely with colleagues; timely and effectively communicates issues to supervisor Minimum Qualifications: Bachelor's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 4+ years of biotechnology/biopharmaceutical industry experience in cell line development OR Master's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 1+ year of biotechnology/biopharmaceutical industry experience in cell line development Sound knowledge of cell culture principles, experience in aseptic techniques required Computer experience in common Microsoft applications (Word, Excel, PowerPoint) is required What we offer: Excellent full time benefits including comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holidays Position is full-time, Monday-Friday, 8 a.m.-5 p.m., with overtime as needed. Candidates currently living within a commutable distance of Cambridge, Massachusetts are encouraged to apply. Eurofins Lancaster Laboratories Professional Scientific Services ® (PSS) is a global, award-winning insourcing solution that places our people at our clients' site dedicated to running and managing laboratory services while eliminating headcount, co-employment and project-management worries. We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR and great place to work best practices, to recruit, hire, train and manage highly qualified scientists to perform laboratory services using our client's quality systems and equipment. Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

Biologics - Upstream Cell Line Development Employee Responsibilities include, but are not limited to: Support the cell line development (CLD) team through participation in transfection, stable selection, cloning, expansion and characterization of mammalian cell lines for clinical and commercial production Perform laboratory experiments using a variety of CLD and cell culture technologies including single cell cloning/clone picking, cell imaging, liquid handling automation and Octet/ELISA-based recombinant protein quantification Support molecular characterization of the lead clonal cell lines for CLD programs including but not limited to mRNA analysis and gene copy number determination Works with departmental and/or cross functional peers to execute on assignments, under limited supervision. Prepares experimental protocols. Contributes significantly to project work which may include multiple projects within functional area. Interprets data independently, and contributes to technical reports Identifies technical issues, and implements solutions under supervision Contributes to the design of new applications/experiments/unit operations in consultation with supervisor. Coordinates within department as well as cross functionally with peers on projects. The Ideal Candidate would possess: Experience in CLD technologies including culture of mammalian cells, single-cell cloning (sorting/clone picking), clonality assessment, and clone screening highly desirable Experience in molecular biology methods including subcloning, northern blot, RT-qPCR/ddPCR and Octet/ELISA-based recombinant protein quantification is desirable Ability to troubleshoot and resolve critical and routine issues using appropriate information Ability to work within department groups/team Ability to manage work load efficiently and in timely manner especially when projects are at a critical stage Proficiency in use of applicable lab equipment and operations; experience in maintaining written records of work in the form of laboratory notebooks (paper or electronic) Ability to report data, present findings to management Minimum Qualifications: Bachelor's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 4+ years of biotechnology/biopharmaceutical industry experience in cell line development OR Master's degree in biochemistry, biology, biotechnology, or related pharmaceutical science; 1+ year of biotechnology/biopharmaceutical industry experience in cell line development Sound knowledge of cell culture principles, experience in aseptic techniques required Computer experience in common Microsoft applications (Word, Excel, PowerPoint) is required What we offer: Excellent full time benefits including comprehensive medical coverage, dental, and vision options Life and disability insurance 401(k) with company match Paid vacation and holidays Position is full-time, Monday-Friday, 8 a.m.-5 p.m., with overtime as needed. Candidates currently living within a commutable distance of Cambridge, Massachusetts are encouraged to apply. Eurofins Lancaster Laboratories Professional Scientific Services ® (PSS) is a global, award-winning insourcing solution that places our people at our clients' site dedicated to running and managing laboratory services while eliminating headcount, co-employment and project-management worries. We infuse our 55-year track record of scientific and laboratory operations expertise, as well as HR and great place to work best practices, to recruit, hire, train and manage highly qualified scientists to perform laboratory services using our client's quality systems and equipment. Eurofins is a M/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

About Us: As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community by leading innovation across our system. Founded by Brigham and Women's Hospital and Massachusetts General Hospital, Mass General Brigham supports a complete continuum of care including community and specialty hospitals, a managed care organization, a physician network, community health centers, home care and other health-related entities. Several of our hospitals are teaching affiliates of Harvard Medical School, and our system is a national leader in biomedical research.We're focused on a people-first culture for our system's patients and our professional family. That's why we provide our employees with more ways to achieve their potential. Mass General Brigham is committed to aligning our employees' personal aspirations with projects that match their capabilities and creating a culture that empowers our managers to become trusted mentors. We support each member of our team to own their personal development-and we recognize success at every step.Our employees use the Mass General Brigham values to govern decisions, actions and behaviors. These values guide how we get our work done: Patients, Affordability, Accountability & Service Commitment, Decisiveness, Innovation & Thoughtful Risk; and how we treat each other: Diversity & Inclusion, Integrity & Respect, Learning, Continuous Improvement & Personal Growth, Teamwork & Collaboration.GENERAL SUMMARY / OVERVIEW: The Gene and Cell Therapy Institute (GCTI) is a newly created system-wide Institute under Mass General Brigham. The Institute will foster a world-class gene and cell therapy program that will leverage ongoing, groundbreaking scientific research efforts across the MGB system. The mission of GCTI is to bring together the community of MGB investigators which can utilize gene and cell therapy platforms to achieve their scientific and clinical goals and improve the health of patients. The Institute will differentiate itself by harnessing the exceptional strengths of clinician scientists, the large and unique patient population, and major discoveries throughout the hospital system to propel MGB as the leader in Gene & Cell therapies. The Abudayyeh-Gootenberg Gene Editing lab at the Mass General Brigham Gene and Cell Therapy Institute is seeking a highly organized and dynamic individual to serve as a manager and principal scientist for a new Gene Editing and Perturbation (GEP) core housed at the GCTI. This unique role provides an opportunity to be a part of a team contributing to the forefront of technology development in gene therapy, cell therapy, and aging research and supporting the entire MGB ecosystem's research and development in the gene editing and genomic perturbation space.This position is designed for a motivated and skilled individual who will be instrumental in managing the GEP's operations. The GEP is a new model, established by the GCTI, to assist researchers both across MGB and external groups with performing gene editing experiments and pooled genetic screens. Successful candidates will play a pivotal role in establishing the core, hiring additional members to assist with core activities, setting up initial services, and working with potential investigators in the MGB ecosystem. Additionally, there is the opportunity to engage in cutting-edge research and collaborations, including but not limited to publishing results, assisting with pre-clinical asset development, and eventually in scale up of reagents for clinical trials. We are looking for someone who thrives in a fast-paced, innovative environment and is passionate about supporting science that makes a difference. The ideal candidate will be highly organized, possess exceptional planning skills, and demonstrate a strong curiosity about the work. Furthermore, existing experience with genome editing, CRISPR, lentiviral preparation, and pooled screening is strongly preferred.PRINCIPAL DUTIES AND RESPONSIBILITIES:Core Management • Oversee daily operations of the GEP core, ensuring efficient workflow and compliance with safety regulations.• Establish systems and infrastructure for accepting orders and billing customers.• Ensure proper and timely production of requested samples.• Setting up initial lab services and activities.• Assist clients with critical know-how for designing and debugging experiments.• Recruiting additional core staff as needed.Scientific Support• Purify lentiviral libraries for pooled genetic screening.• Transduce cell lines with libraries.• Harvest DNA and analyze NGS results of pooled screens.• Perform cell sorting as needed to read out screens.• Handle primary cell lines for genome editing experiments.• Design and test guide RNAs for CRISPR technologies, including nucleases, CRISPRi, base editing, and prime editing.• Delivery genome editing reagents to cell lines and primary cells using diverse delivery technologies, including DNA lipofection, mRNA delivery, viral transduction, and electroporation.Qualifications • PhD in n a relevant scientific discipline.• Experience with genome editing and CRISPR technologies.• Experience with genome-wide screening.• Prior experience in lab management and leadership is helpful.• Strong organizational skills and the ability to multitask effectively.• Excellent communication skills, both written and verbal.• Proficiency in office and lab software, including Microsoft Office Suite and laboratory information management systems (LIMS).• Knowledge of laboratory safety and compliance regulations.• Demonstrated ability to work independently as well as part of a team.SKILLS/ ABILITIES/ COMPETENCIES:• High degree of computer literacy• Sound analytical and organizational skills.• Requires good oral and written communication skills.• Must be able to logically and effectively structure tasks and set priorities.• Ability to identify problems in the lab and trouble-shoot solutions.• Independent drive and motivationEEO Statement Mass General Brigham is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

Harvard UniversityDescription: 02-Apr-2024Bio-Soft Lithography EngineerFaculty of Arts and Sciences 65471BRPosition DescriptionThe Center for Nanoscale Systems (CNS) at Harvard University seeks an enthusiastic, scientifically curious individual with a strong growth mindset to work within the Imaging and Analysis Group as a Scientist focused primarily on teaching and supporting researchers about microfluidic device fabrication and cell culture techniques. CNS is an open, shared-use facility that serves all of Harvard as well as external academic and industrial users. CNS typically supports more than 1,700 users annually. Working under the supervision of the Imaging and Analysis Facility Manager, and in coordination with the otherImaging and Analysis staff at CNS, this person will assist in the day-to-day operation of the soft lithography fabrication laboratory at the Science and Engineering Complex in Allston, MA the soft lithography fabrication laboratory and the cell culture laboratory both in the Laboratory for Science and Engineering Cambridge, MA.Day to day operations of these labs include teaching users safe and correct tool operation and working with users on experimental design, device design, sample preparation, data analysis, and data interpretation.This person will also be responsible for overseeing CNS’s compliance with Harvard and government safety laws and regulations. Their duties include coordinating with the CNS safety officer to identify potential risks, implementing policies and procedures to uphold safety regulations and monitoring their workplace for adherence to those policies and procedures.The candidate should be excited about teaching and assisting researchers in their scientific endeavors. The mission of this position is to enable and support other researchers' scientific and engineering endeavors. Strong teaching and interpersonal skills, e.g. approachability, patience, adaptability, confidence, ability to provide clear and concise explanations of complicated concepts, creativity, critical thinking, etc. are essential for this position.There is also a fair component of equipment maintenance, equipment trouble shooting, and general shared use lab management in the day-to-day operations of these labs.The candidate needs to be comfortable in a dynamic and fast paced environment assisting users on a wide variety of different types of projects from all across the range of biological and physical sciences. The candidate must have the willingness and the ability to quickly become an expert on a variety of topics. Being a science generalist is key to success in this position.The incumbent will become resources for the CNS scientific community and must have strong written and verbal communication skills to convey information effectively and efficiently.The candidate will also on occasion perform work for remote CNS users. Detailed record keeping of instrument activity, experimental results, maintenance, and repair logs, and authoring if standard operating procedures is expected.Basic Qualifications Bachelor’s degree in a scientific or engineering discipline and at least two years of relevant work experience; OR A minimum of seven years of relevant work experience or equivalent combination of education and experienceAdditional Qualifications and SkillsThe candidate should be self-motivated and able to work independently with a strong desire to acquire on-the-job training, to succeed, and to develop intellectual and practical professional skills.Excellent verbal and written skills required.Demonstrated ability to work well in teams and with graduate and undergraduate students is essential.The candidate must have significant experience in a variety of laboratory environments and be fully comfortable working in a lab environment on a wide variety of tools and projects. Expertise in microfluidic device design and fabrication.Expertise in aseptic techniques for cell culturing.Familiarity with rapid prototyping such as laser cutting and 3D printing.Familiarity with safe handling of nanoparticles.Familiarity with gas adsorption for surface area and porosity measurements, and chemisorption and dynamic adsorption studies for characterizing active surfaces.Familiarity with fluorescence plate readers, dynamic light scattering (DLS) measurements, zeta potential measurements, freeze dryers, ball mills, stylus profilers, optical microscopes.Physical RequirementsMust be able to work in an imaging facility, cleanroom, biological, chemical, and characterization laboratory environments.Will work around compressed gases, cryogens, ovens, acids, bases, oxidizers, solvents, vacuum pump oils, and other chemicals. Must be very dexterous; may be required to work on large and small assemblies.Ability to lift 50 lbs on occasion.Working ConditionsLaboratories (BL2, BL], cleanroom) and office setting.Additional InformationThis work is performed on campus in Cambridge and Allston, MAWork Format DetailsThis position is based primarily on-campus, in Massachusetts. This may include in-person during emergency situations (if applicable). Additional details will be discussed during the interview process. Certain visa types may limit work location. Individuals must meet work location sponsorship requirements prior to employment.BenefitsWe invite you to visit Harvard's Total Rewards website (https://hr.harvard.edu/totalrewards) to learn more about our outstanding benefits package, which may include: Paid Time Off: 3-4 weeks of accrued vacation time per year (3 weeks for support staff and 4 weeks for administrative/professional staff), 12 accrued sick days per year, 12.5 holidays plus a Winter Recess in December/January, 3 personal days per year (prorated based on date of hire), and up to 12 weeks of paid leave for new parents who are primary care givers. Health and Welfare: Comprehensive medical, dental, and vision benefits, disability and life insurance programs, along with voluntary benefits. Most coverage begins as of your start date. Work/Life and Wellness: Child and elder/adult care resources including on campus childcare centers, Employee Assistance Program, and wellness programs related to stress management, nutrition, meditation, and more. Retirement: University-funded retirement plan with contributions from 5% to 15% of eligible compensation, based on age and earnings with full vesting after 3 years of service. Tuition Assistance Program: Competitive program including $40 per class at the Harvard Extension School and reduced tuition through other participating Harvard graduate schools.Tuition Reimbursement: Program that provides 75% to 90% reimbursement up to $5,250 per calendar year for eligible courses taken at other accredited institutions. Professional Development: Programs and classes at little or no cost, including through the Harvard Center for Workplace Development and LinkedIn Learning.Commuting and Transportation: Various commuter options handled through the Parking Office, including discounted parking, half-priced public transportation passes and pre-tax transit passes, biking benefits, and more. Harvard Facilities Access, Discounts and Perks: Access to Harvard athletic and fitness facilities, libraries, campus events, credit union, and more, as well as discounts to various types of services (legal, financial, etc.) and cultural and leisure activities throughout metro-Boston.Job FunctionResearch Department Office LocationUSA - MA - Cambridge Job CodeR1057P Research Core Scientist III Work FormatOn-Site Sub-UnitSciences Salary Grade057DepartmentCenter for Nanoscale SystemsUnion00 - Non Union, Exempt or Temporary Time StatusFull-time Pre-Employment ScreeningEducation, IdentityCommitment to Equity, Diversity, Inclusion, and BelongingHarvard University views equity, diversity, inclusion, and belonging as the pathway to achieving inclusive excellence and fostering a campus culture where everyone can thrive. We strive to create a community that draws upon the widest possible pool of talent to unify excellence and diversity while fully embracing individuals from varied backgrounds, cultures, races, identities, life experiences, perspectives, beliefs, and values.EEO StatementWe are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.LinkedIn Recruiter Tag (for internal use only)#LI-KO1 PI239056928

The Role:The successful candidate will partner with a multidisciplinary team to develop internal capabilities and perform screens to discover and characterize antigen variants with improved surface expression and thermal stability. The goal is to use library construction and verification coupled with mammalian display to enable campaigns for multiple targets of interest. Successful lead generation will allow for subsequent testing in pre-clinical models and subsequently in the clinic. The position offers significant scientific growth opportunities in several areas including vaccine development, infectious disease biology, protein engineering and automation.Responsibilities:You will work in close collaboration with research leadership and a team of peers to identify and prioritize targets for screening. Success will require a collaborative and proactive approach with a clear focus on effective team work. Excellent laboratory and organizational skills combined with insightful and decisive data analysis will be required to ensure that program team deadlines are consistently reached. Presentation in program team and departmental meetings will be required to communicate results and recommendations to stakeholders. Further responsibilities include report and protocol writing, reagent generation and archiving, equipment onboarding, inventory maintenance and data archiving (ELN/LIMS).Skill Set: Experience with both library screening and mammalian display are essential and ideally include: molecular biology methods for multiple library generation strategies (including key PCR methods for library construction in addition to rigorous cloning methods for efficient vector library assembly and verification, familiar with random mutagenesis and DNA extraction technique), lentivirus production and transduction, mammalian cell culture, FACS and NGS sequencing methods and associated data analysis techniques. Additional skills to support downstream characterization as needed would be beneficial and could include: protein expression and purification using FPLC systems and biophysical characterization methods (SEC-MALS, DSF, and biosensor techniques including BLI and SPR.Here's What You'll Do: Collaborate with bioinformatics team to translate library design concepts into experimental strategy with associated timelines.Collaborate with wet lab team members to further develop screening strategy and assign responsibilities to ensure timely progress balanced with other activities.Perform library generation and cloning, perform cell staining, use FACS to isolate clones with improved expression, prepare DNA samples for NGS, coordinate with NGS team to acquire and analyze data, archive all data in accessible formats.Collaborate with manager to integrate experimental design and outcomes for presentation to team and program members, make recommendations based on data and program team feedback.Utilize an ELN to capture experimental results and participate in LIMS integration.Assist in reagent ordering and inventory in addition to procurement and maintenance of laboratory equipment.Here's What You'll Bring to the Table:Exceptional Ph.D. in immunology, bacteriology, virology, molecular biology, biochemistry or biophysics ideally with industry experience.Outstanding laboratory experience and knowledge in various library construction and screening workflows, experimental design, data analysis and ability to transition hypotheses into data and scientific insights.Knowledge of mRNA biotechnology, bacteriology, virology, immunology, protein structure and vaccine design is a plus.Candidates will be curious in exploring new paths for drug discovery, bold in proposing creative experimental designs and ideas, will work collaboratively with multifunctional teams and be relentless in pursuing successful outcomes.Candidates must possess excellent data management and verbal/written communication skills, have excellent track record in experimental performance, evaluate and process data, present results in a clear, concise and timely manner, and assist with the preparation of final written reports.Ability to work independently and as part of a team in a highly dynamic, fast-paced, matrixed environment with evolving priorities.Ability to collaborate with colleagues to achieve scientific and career goals aligned with business objectives.Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:Highly competitive and inclusive medical, dental and vision coverage optionsFlexible Spending Accounts for medical expenses and dependent care expensesLifestyle Spending Account funds to help you engage in personal enrichment and self-care activitiesFamily care benefits, including subsidized back-up care options and on-demand tutoringFree premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipmentAdoption and family-planning benefitsDedicated care coordination support for our LGBTQ+ communityGenerous paid time off, including:• Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafterGenerous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning toolsModerna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit optionsComplimentary concierge service including home services research, travel booking, and entertainment requestsFree parking or subsidized commuter passesLocation-specific perks and extras! About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.Moderna is a smoke-free, alcohol-free and drug-free work environment.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. (EEO/AAP Employer) #LI-JW2-

The Role:Moderna is seeking a Director of Clinical Biomarkers to serve as a scientific leader and point of contact for clinical teams in the Infectious Disease (ID) space with responsibilities for developing and driving pivotal biomarker plans across clinical stage ID programs. This position reports to Moderna's Sr. Director of Infectious Disease, Clinical Biomarkers. The Director will work collaboratively across multiple clinical teams to ensure strategy, planning, execution and data delivery of biomarker lab data for early and late phase infectious disease vaccine clinical trials conducted by Moderna.Here's What You'll Do: Partner with a team of dedicated and senior Clinical Biomarker scientists on the science and bioanalytical assays for Moderna's early and late phase infectious disease vaccine programsCollaborate with clinical and research teams to define overall biomarker strategies for high priority programsOversee biomarker plans and strategy with input from research and clinical leads for ID studiesResponsible to ensure assay labs complete appropriate development, qualification or validation of biomarker assays in order to execute the clinical biomarker plan on time and with good quality for ID clinical programsEnsure timely and efficient delivery of all biomarker operational aspects across multiple ID clinical trialsDevelop and provide operational input and recommendations into all study related documentation (including protocol, lab manual, informed consent form, IB and regulatory filings) and processes, and ensure collection, delivery and analysis of biosamples in compliance with these documents as well as GCP/ICHServe as a primary point of contact for biomarker operations across ID teams, and with external collaborators, assay labs and CROs.Contribute to the identification and selection of biomarker vendors and aid in building the strategy for the selection of those vendorsServe as the primary point of contact for interpretation and troubleshooting of bioanalytical data for high priority programsLead biomarker sub teams and participate in clinical team meetingsParticipate in committees and work streams that support process and procedure for standardized language, biomarker usage, and data transfer and collectionHere's What You'll Bring to the Table:PhD (with at least 4 years pharmaceutical/biotechnology experience) in a related science with a focus on infectious disease.Experience leading a team of clinical translational or biomarker leaders and deep understanding of the role of clinical biomarkers across drug development from early phase through licensureDeep understanding of the regulatory expectations for pivotal biomarkers in clinical trialsSolid experience in the application of biomarkers during development of assets required including experience with clinical translational research, development, validation and implementation of biomarkers in the ID space.Experience in Infectious disease programs (Ex: Human respiratory viruses / Human herpes viruses / HIV / Human Flaviviruses / Bacterial diseases is highly desirable.Experience in Lyme, Pertussis, Group A Streptococcus or other bacterial diseases is a plus.Experience in managing third party assay laboratories, collaborations and budget management.Strong communication and project management skillsModerna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:Highly competitive and inclusive medical, dental and vision coverage optionsFlexible Spending Accounts for medical expenses and dependent care expensesLifestyle Spending Account funds to help you engage in personal enrichment and self-care activitiesFamily care benefits, including subsidized back-up care options and on-demand tutoringFree premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipmentAdoption and family-planning benefitsDedicated care coordination support for our LGBTQ+ communityGenerous paid time off, including:• Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafterGenerous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning toolsModerna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit optionsComplimentary concierge service including home services research, travel booking, and entertainment requestsFree parking or subsidized commuter passesLocation-specific perks and extras! About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.Moderna is a smoke-free, alcohol-free and drug-free work environment.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. (EEO/AAP Employer) #LI-JL3-

The Role:The Infectious Diseases Research (IDR) Team at Moderna is seeking a self-motivated and adaptable Principal Research Associate with strong experience working with murine models and in vivo research techniques to support the development of novel vaccines and therapeutics. This position will contribute across all ID research programs through the performance and development of in vivo based experiments in biosafety level 1, 2 and 3 environment.The candidate will support the IDR comparative medicine team interfacing with multiple departments within IDR. The individual will help to ensure the accurate and quality execution of in-vivo based experimental programs.Here's What You'll Do:Work closely with scientists and the Comparative Medicine Director to ensure quality and compliance of all in vivo based experimentsAssist with, oversee and ensure adequate tools to deliver efficient team logistics, scheduling, and resourcesCarry out technical procedural work with laboratory animal species with particular competency in mice.Ability to understand and operate specialized in vivo based equipment such as common imaging modalities.Process samples according to specific criteria, store and/or ship appropriatelyAssist with ensuring facility and animal housing rooms are adequately equipped and suppliedAssist with all aspects of experimental planning and logisticsMaintain full compliance with regulatory requirements including protocols, SOPs, and other working documents. Contribute towards document writing and implementation of new processes.Interpret, summarize, and report on experimental data as necessary.Assist with or oversee creation of databases, logs and appropriate software selection for given functions.Here's What You'll Bring to the Table:B.S. with a minimum of 5 years of relevant experience working with laboratory animals' speciesExtensive experience carrying out technical procedural work involving murine modelsKnowledge and hands-on experience working with in the regulatory framework for compliant in-vivo research experimentsAttention to detail, ability to think ahead and strong communication skillsAbility to work independently with minimal supervisionExcellent record keeping and data management skillsFamiliarity with ABSL2 working practices and procedures is strongly preferredExperience working in ABSL3 environments is a major plusCandidate will be curious in exploring new path for drug discovery, bold in proposing creative experimental designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomesModerna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:Highly competitive and inclusive medical, dental and vision coverage optionsFlexible Spending Accounts for medical expenses and dependent care expensesLifestyle Spending Account funds to help you engage in personal enrichment and self-care activitiesFamily care benefits, including subsidized back-up care options and on-demand tutoringFree premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipmentAdoption and family-planning benefitsDedicated care coordination support for our LGBTQ+ communityGenerous paid time off, including:• Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafterGenerous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning toolsModerna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit optionsComplimentary concierge service including home services research, travel booking, and entertainment requestsFree parking or subsidized commuter passesLocation-specific perks and extras! About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.Moderna is a smoke-free, alcohol-free and drug-free work environment.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. (EEO/AAP Employer) #LI-JW2-

Harvard UniversityTitle: Therapeutics Graduate Program Curriculum Fellow School: Harvard Medical School Department_Area: Therapeutics Graduate Program Position Description: The Harvard Medical School Curriculum Fellows Program ( HMS CFP ) welcomes applications for a Therapeutics Graduate Program Curriculum Fellow ( TGP CF) for the HMS Therapeutics Initiative and the HMS Office for Research Operations and Global Programs. This postdoctoral program targets early-career scientist-educators, emphasizing curriculum development, teaching, and educational programming in the biological and biomedical sciences.The TGP Curriculum Fellow collaborates with a diverse cohort of Curriculum Fellows, leveraging individual expertise while closely engaging with Harvard Medical School faculty and administration to craft, implement, and assess evidence-based graduate training. Fellows benefit from mentorship and career guidance, nurturing their growth as educators and facilitating success across various education-focused careers. Further details are available on our website (https://curriculumfellows.hms.harvard.edu/).The mission of the Therapeutics Graduate Program ( TGP ) is to: (1) provide students with the intellectual, scientific, laboratory, computational, and professional skills needed to excel in academic and industrial careers related to therapeutics discovery and development; (2) create and sustain a diverse, inclusive, equitable, and engaged community of students and faculty with shared interests in therapeutics; and (3) provide a safe, respectful, and stimulating environment for training and professional development. Our program opens doors to well-paid jobs and leadership trajectories in pharmacological sciences and drug discovery research in academia and industry.The CF will report directly to and receive mentorship from Dr. David Golan, Professor of Biological Chemistry and Molecular Pharmacology, George R. Minot Professor of Medicine, and HMS Dean for Research Operations and Global Programs, and Dr. Aimee Hollander, the Curriculum Fellows Program Director. The primary responsibilities of the TGP Curriculum Fellow are expected to include: Partner with faculty on the TGP's required courses in pharmacology and drug discovery, including but not limited to: BCMP 301qc, an intensive January term course; BCMP 236, a full semester course; and CELLBIO 302qc, a half semester course; as well as short courses and workshops addressing advanced and specialized topics. Collect and analyze student outcomes for TGP required courses to evaluate the effectiveness of these courses, resulting in a written report(s) provided to the course directors. Facilitate and contribute to development of a new course in cell and gene therapy based on modern best teaching practices. Contribute to the TGP's NIGMS Pharmacological Sciences T32 training grant, including gathering data for progress reports, supplemental funding, or renewal. Collaborate with colleagues in the TGP and in the Office for Postdoctoral Fellows on various workshops, community events, and related programming. The TGP CF is expected to attend and participate in TGP community events. Actively participate in the TGP leadership group, support faculty directors, and work with program manager to facilitate a dynamic, engaging, collaborative, and supportive environment for the program and its activities. Additionally, the TGP Curriculum Fellow will have specific responsibilities to the CFP : Take required courses, including Teaching 100 and Teaching 101. Participate in weekly CFP group meetings and pedagogical journal clubs. Present at university-wide workshops on curricular and pedagogical topics. Assist in developing the curriculum for the NIH -mandated Responsible Conduct of Science ( RCOS ) course. Assist with the organization of the Graduate Science Education Series ( GSES ), https://curriculumfellows.hms.harvard.edu/graduate-science-education-series BASIC QUALIFICATIONS :Candidates are expected to have a PhD or equivalent degree in biomedical sciences, preferably related to therapeutic science, pathophysiology, pharmacology, or disease-related research along with teaching experience. Candidates who are currently finishing their doctoral work but have not yet graduated are encouraged to apply.Qualified candidates will be evaluated based upon their: Demonstrated interest or experience with teaching and/or curriculum development in higher education settings Interest and/or experience in teaching and developing curriculum in an asynchronous online environment Ability to research and learn new topics related to therapeutic science, and to apply that knowledge for curriculum development or improvement Organizational and written and oral communication skills Experience in project planning and implementation from conception to completion Ability to support collaborations across departments in a fast-paced academic environment Ability to work independently as well as part of a small, coordinated team The ideal start date for this Curriculum Fellow is approximately early-mid June, 2024. This is a hybrid position and the candidate will be expected to work in person on the HMS campus in Boston, MA 2-3 days per week. The CF appointment is renewable annually for a maximum of three years and is non-tenure-track.Application Deadline & Instructions:Applications are being reviewed on a rolling basis. Once you apply through the portal, please email [email protected] to alert the hiring team that you've applied. Below are the required application materials needed to apply: A cover letter that addresses your interest in and qualifications for the position. Please highlight your experience in curriculum development, particularly related to drug discovery, therapeutic science, pharmacology, physiology, biochemistry, or cell biology in your cover letter. A curriculum vitae. A teaching statement. The teaching statement is an opportunity to describe your philosophy of teaching in the context of your own experiences. A discussion of diversity, equity, and inclusion is an important component of the teaching statement. Submissions will be evaluated according to the guidelines found on our website, here, https://curriculumfellows.hms.harvard.edu/teaching-statement-guidelines The names and contact information of three professional references. If you have any questions specific to the program or fellowship, please email: [email protected]. Basic Qualifications: Candidates are expected to have a PhD or equivalent degree in biomedical sciences, preferably related to therapeutic science, pathophysiology, pharmacology, or disease-related research along with teaching experience. Candidates who are currently finishing their doctoral work but have not yet graduated are encouraged to apply. Contact Information: Bethany Krevat Curriculum Fellows Program Coordinator Contact Email: [email protected] Equal Opportunity Employer: We are committed to cultivating an inclusive workplace culture ( https://hr.fas.harvard.edu/inclusive-culture ) of faculty, staff, and students with diverse backgrounds, styles, abilities, and motivations. We appreciate and leverage the capabilities, insights, and ideas of all individuals. Harvard Medical School Mission and Community Values: https://hms.harvard.edu/about-hms/campus-culture/mission-community-values-diversity-statement We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions or any other characteristic protected by law. Minimum Number of References Required: 3 Maximum Number of References Allowed: 3 Keywords: therapeutics, biomedical science, Biological Chemistry, biochemistry, Molecular Pharmacology, teaching, faculty, postdoc, curriculum Supplemental Questions: Required fields are indicated with an asterisk (*). * How did you hear about this position? Academic Careers online Bay State Banner Chronicle of Higher Education Harvard Department Website Higher Education Recruitment Consortium (HERC) HigherEdJobs Inside Higher Ed Nomination Letter Professional Conference Professional Organization or Listserv Referred by a colleague * Will you hold a doctoral degree by the date indicated in the job advertisement? Yes No PI239890234

Company DescriptionEurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.In 2020, Eurofins generated total revenues of EUR € 5.4 billion, and has been among the best performing stocks in Europe over the past 20 years.Job DescriptionExecute testing of assigned analysis type for routine sample submissions for chemical and physical properties characterization of drug substance and drug productPerforming dissolution testing to inform formulation development are essentialIdentify and help to resolve equipment and basic test method issuesProvide feedback to client on the performance of existing assays / test methodsExcellent verbal and written communication skillsGood problem-solving abilities;ability to excel in a dynamic project environment.QualificationsBS in science (Chemistry, Pharmaceutics, Biopharmaceutics, Pharmaceutical sciences, or related science degree)2+ years of directly related experiencePrior knowledge and lab experience with dissolution testingPrior knowledge and lab experience with HPLCPrior knowledge and lab experience with formulation developmentPrior knowledge and lab experience with drug delivery and pharmacokinetics (preferred)Additional InformationPosition is full-time, Monday - Friday 8:00am - 5:00pm.Candidates currently living within a commutable distance of Cambridge,MAare encouraged to apply.Excellent full time benefits including comprehensive medical coverage, dental, and vision options.Life and disability insurance401(k) with company matchPaid vacation and holidaysEurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.Eurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

Company DescriptionEurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.In 2020, Eurofins generated total revenues of EUR € 5.4 billion, and has been among the best performing stocks in Europe over the past 20 years.Job DescriptionExecute testing of assigned analysis type for routine sample submissions for chemical and physical properties characterization of drug substance and drug productPerforming dissolution testing to inform formulation development are essentialIdentify and help to resolve equipment and basic test method issuesProvide feedback to client on the performance of existing assays / test methodsExcellent verbal and written communication skillsGood problem-solving abilities;ability to excel in a dynamic project environment.QualificationsBS in science (Chemistry, Pharmaceutics, Biopharmaceutics, Pharmaceutical sciences, or related science degree)2+ years of directly related experiencePrior knowledge and lab experience with dissolution testingPrior knowledge and lab experience with HPLCPrior knowledge and lab experience with formulation developmentPrior knowledge and lab experience with drug delivery and pharmacokinetics (preferred)Additional InformationPosition is full-time, Monday - Friday 8:00am - 5:00pm.Candidates currently living within a commutable distance of Cambridge,MAare encouraged to apply.Excellent full time benefits including comprehensive medical coverage, dental, and vision options.Life and disability insurance401(k) with company matchPaid vacation and holidaysEurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.Eurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.