Systems Engineering Salary in New Haven, CT

Job ID: 492010Tilcon Connecticut Inc., a CRH company, has played a vital role in building infrastructure around our state, serving the market from 23 locations throughout Connecticut. As a leading supplier of quality crushed stone, hot mix asphalt, and ready mix concrete, Tilcon Connecticut has supported the construction of superior roads, buildings and bridges. The most respected name in the construction industry, from the quarry to the road, Tilcon Connecticut does it all!Are you looking for opportunities and benefits of a large corporation with a small company feel? Then Tilcon Connecticut Inc. and CRH is the company for you! If you're up for a rewarding challenge, we invite you to take the first step and apply today!Position Overview A Parts Clerk is responsible for securing parts and supplies for the repair and maintenance of mobile and plant equipment.Key Responsibilities (Essential Duties and Functions) Support Equipment Manager, Equipment Supervisor and Shop Foreman and technicians as needed. Coordinate parts securement from various vendors for equipment maintenance / repair Create purchase orders and process invoices with proper coding and filing Receive and process all parts requests, place orders with vendors, ensure timely delivery of incoming parts ,receive and distribute to mechanics or other LOB's Work with vendors to correct invoice discrepancies Manage parts room inventory to correct inventory levels and costs Off load incoming freight from trucks using company fork lift truck Work with vendors to make sure we receive all credits when core parts are returned Track and report daily fuel inventory Greet general public and vendor sales persons. Work closely with equipment team on various projects or additional requests as they arise Answer phones Viewpoint / CMMS / Infield Become familiar with Tilcon CRH maintenance and computer systems Input work requests and work orders into operating systems. Additional Responsibilities Display a professional and courteous attitude to co-workers, supervisors, and the general public at all times. Must be willing to work weekends when necessary. Report to the assigned work place and ready to begin work at the designated start time. Adhere to any and all state and federal regulations, if applicable, as set forth by the Occupational Safety and Health Administration (OSHA), Mine Safety and Health Administration (MSHA), or any other regulatory agency. Strict adherence to safety requirements and procedures as outlined in the Environmental, Health & Safety Manual. Strict adherence to Tilcon Connecticut, Inc. policies and procedures as outlined in the Employee Manual. Willingness to work in a team environment and assist co-workers or supervisors with other duties as required. Qualifications To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. Education/Experience High school diploma or General education degree (GED) and/or 2-5 years relevant experience in similar job position. Valid fork truck operating certificate Work Requirements Ability to communicate sufficiently to be able to convey and exchange ideas, and to give and receive detailed verbal instructions. Ability to apply common sense understanding to carry out instructions furnished in written, oral, or diagram form. Ability to deal with problems involving several concrete variables in standardized situations. Maintain a clean and organized parts/ work area Knowledge/Skill Requirements Individual must possess excellent computer skills and be proficient with Windows, Microsoft Excel, Word Physical Requirements The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.This chart outlines the physical requirements necessary to perform the duties of this job. Continuous Frequency Occasionally Not Applicable Bend X Kneel X Squat X Climb X Stand X Walk X Sit X Reach X Drive X Fine Motor X Repetitive Motion X Right X Left XThe employee must occasionally lift and/or move up to 10 pounds.Continuous Frequency Occasionally Not Applicable 0 - 10 lbs. X 10-25 lbs. X 25-50 lbs. X 50-100 lbs. XWork Environment The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.While performing the duties of this job, the employee is regularly required to work on a computer using fingers and hands to make key strokes. The employee frequently is required to sit, stand, and walk. The work environment is occasionally exposes the worker to moderate noiseThis chart outlines the potential work environment the employees may be exposed to while performing the duties of this job. Continuous Frequency Occasionally Not Applicable Hot Weather X Cold Weather X Wet Weather X Exposed to Noise X Exposed to High Heat X Moving Equipment X Working with Others XWhat CRH Offers You Highly competitive base pay Comprehensive medical, dental and disability benefits programs Group retirement savings program Health and wellness programs A diverse and inclusive culture that values opportunity for growth, development, and internal promotion About CRHCRH has a long and proud heritage. We are a collection of hundreds of family businesses, regional companies and large enterprises that together form the CRH family. CRH operates in a decentralized, diversified structure that allows you to work in a small company environment while having the career opportunities of large international organization.If you're up for a rewarding challenge, we invite you to take the first step and apply today! Once you click apply now, you will be brought to our official employment application. Please complete your online profile and it will be sent to the hiring manager. Our system allows you to view and track your status 24 hours a day. Thank you for your interest! Tilcon Connecticut Inc., a CRH Company, is an Affirmative Action and Equal Opportunity Employer.EOE/Vet/Disability--If you want to know more, please click on this link. Date: Apr 21, 2024 Nearest Major Market: New Haven Nearest Secondary Market: Hartford Job Segment: Forklift, Clerical, Construction, Manufacturing, Administrative, Engineering

The EHS Coordinator & Quality Engineer will be responsible for the following:Support all QHSE functions which are applicable according to the requirements of the site's integrated management system (IMS) and those of ISO 9001, 14001, and 45001.Develop, implement, and maintain company policies and procedures related to quality, health, safety, and environmental management.Conduct risk assessments and hazard analyses to identify potential threats to employee safety, product quality, and environmental sustainability.Coordinate employee training programs to ensure compliance with safety protocols, quality standards, and environmental regulations.Lead incident investigations and root cause analyses to identify underlying factors contributing to accidents, near misses, or quality issues.Implement corrective and preventive actions to address identified deficiencies and prevent recurrence of incidents.Conduct regular audits and inspections of manufacturing facilities to assess compliance with QHSE standards and regulations.Monitor and analyze key performance indicators (KPIs) related to quality, health, safety, and environmental performance, and recommend improvements as needed.Collaborate with cross-functional teams to promote a culture of safety, quality, and environmental stewardship throughout the organization.Serve as the primary point of contact for regulatory agencies, ensuring compliance with all applicable laws, regulations, and permits.Prepare reports and presentations to communicate QHSE performance, initiatives, and recommendations to senior management and stakeholders.MPI does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity or expression, national origin, age, disability, veteran status, marital status, or based on an individual's status in any group or class protected by applicable federal, state or local law. MPI encourages applications from minorities, women, the disabled, protected veterans and all other qualified applicants.The ideal EHS Coordinator & Quality Engineer will have the following qualifications:Bachelor of Science in Occupational Health & Safety, Environmental Science, Engineering, or a related fieldMasters degree a plus but not required ISO 14001 experience is required Strong communication skills 2+ years of manufacturing experience required and experience with ISO 9001 is a plus

This is what you will do: This position will lead research, design and implement scientific studies to enable the drug product (DP) process development, characterization, clinical manufacturing, and commercial validation of parenteral/injectable biologic products. Lead and support execution of stability studies, data processing, compiling and presentation of results supporting late-stage clinical activities as well as preparation for PPQ. Develop a variety of manufacturing unit operations including, drug substance (DS) freeze/thaw, compounding/mixing, sterile filtration, drug product filling of vials/syringes, visual inspection, and DS/DP transportation. A general understanding of protein chemistry and/or the ability to run biopharmaceutical assays in a laboratory is preferred.The role will lead manufacturing technology transfer activities in preparation for DS and DP PPQs, sending/receiving site process gap analysis, process FMEAs (failure mode and effects analysis), change control owner/leader, master batch record review, as well as leading at-scale/full scale process development studies, and authoring protocols, and reports. In addition, will support deviation investigations, change controls, and CAPAs using electronic Quality system. The candidate will also provide clinical and commercial manufacturing site support including but not limited to periodic meetings, action item owner, and in-person on-site manufacturing support. Interact regularly with multi-functional staff from Analytical Sciences & Quality Control, Drug Substance Process Development, Manufacturing Technical Services, Quality Assurance, and/or CMC Regulatory Affairs to support progress of the program and preparation of source documentation supporting BLA.You will be responsible for: Own the design and implement studies for Alexion pharmaceuticals' clinical drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sitesLead progression of projects with multi-functional collaborators, as well as understand the implications of project activities and decisions with minimal directionPrioritizing multiple tasks and projects independently and as part of the teamAuthor SOPs, study protocols and technical reportsParticipate in multi-functional development teams representing Injectable Drug Product DevelopmentMaintain knowledge of current trends in drug product manufacturing processes, manufacturing equipment and single use systems as well as associated global regulatory expectations and scientific principles and theories. Train other peers as assigned in areas of expertiseActively participate in department and team meetings including assuming ownership and delivering on assign action itemsDevelop presentations for meetings with internal and external partnersYou will need to have:Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or relevant Engineering/Life Sciences field with 4+ years of relevant experience or Master's degree with 3+ years of relevant work experienceDedicated initiative to find resolution for technical challengesExcellent interpersonal, collaborative and communication skillsThe duties of this role are conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.We would prefer for you to have:Scientific and practical knowledge of protein biochemistry and/or drug product process developmentPrevious experience in bio-therapeutics development as well as relevant knowledge of cGMP and Quality expectations for PPQs and BLAScientific understanding of protein stability, thermodynamics, mechanism of protein degradation, bio-therapeutics drug formulation development and analytical tools used to test formulations is a plusHigh level proficiency in MS Office software including Word, Excel, Outlook, Visio, and PowerPointExpectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world!AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

This is what you will do: This position will lead research, design and implement scientific studies to enable the drug product (DP) process development, characterization, clinical manufacturing, and commercial validation of parenteral/injectable biologic products. Lead and support execution of stability studies, data processing, compiling and presentation of results supporting late-stage clinical activities as well as preparation for PPQ. Develop a variety of manufacturing unit operations including, drug substance (DS) freeze/thaw, compounding/mixing, sterile filtration, drug product filling of vials/syringes, visual inspection, and DS/DP transportation. A general understanding of protein chemistry and/or the ability to run biopharmaceutical assays in a laboratory is preferred.The role will lead manufacturing technology transfer activities in preparation for DS and DP PPQs, sending/receiving site process gap analysis, process FMEAs (failure mode and effects analysis), change control owner/leader, master batch record review, as well as leading at-scale/full scale process development studies, and authoring protocols, and reports. In addition, will support deviation investigations, change controls, and CAPAs using electronic Quality system. The candidate will also provide clinical and commercial manufacturing site support including but not limited to periodic meetings, action item owner, and in-person on-site manufacturing support. Interact regularly with multi-functional staff from Analytical Sciences & Quality Control, Drug Substance Process Development, Manufacturing Technical Services, Quality Assurance, and/or CMC Regulatory Affairs to support progress of the program and preparation of source documentation supporting BLA.You will be responsible for: Own the design and implement studies for Alexion pharmaceuticals' clinical drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sitesLead progression of projects with multi-functional collaborators, as well as understand the implications of project activities and decisions with minimal directionPrioritizing multiple tasks and projects independently and as part of the teamAuthor SOPs, study protocols and technical reportsParticipate in multi-functional development teams representing Injectable Drug Product DevelopmentMaintain knowledge of current trends in drug product manufacturing processes, manufacturing equipment and single use systems as well as associated global regulatory expectations and scientific principles and theories. Train other peers as assigned in areas of expertiseActively participate in department and team meetings including assuming ownership and delivering on assign action itemsDevelop presentations for meetings with internal and external partnersYou will need to have:Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or relevant Engineering/Life Sciences field with 4+ years of relevant experience or Master's degree with 3+ years of relevant work experienceDedicated initiative to find resolution for technical challengesExcellent interpersonal, collaborative and communication skillsThe duties of this role are conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours.We would prefer for you to have:Scientific and practical knowledge of protein biochemistry and/or drug product process developmentPrevious experience in bio-therapeutics development as well as relevant knowledge of cGMP and Quality expectations for PPQs and BLAScientific understanding of protein stability, thermodynamics, mechanism of protein degradation, bio-therapeutics drug formulation development and analytical tools used to test formulations is a plusHigh level proficiency in MS Office software including Word, Excel, Outlook, Visio, and PowerPointExpectation of working in the office 4 days a week statement: When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world!Date Posted26-Apr-2024Closing Date30-Jul-2024Alexion is proud to be an Equal Employment Opportunity and Affirmative Action employer. We are committed to fostering a culture of belonging where every single person can belong because of their uniqueness. The Company will not make decisions about employment, training, compensation, promotion, and other terms and conditions of employment based on race, color, religion, creed or lack thereof, sex, sexual orientation, age, ancestry, national origin, ethnicity, citizenship status, marital status, pregnancy, (including childbirth, breastfeeding, or related medical conditions), parental status (including adoption or surrogacy), military status, protected veteran status, disability, medical condition, gender identity or expression, genetic information, mental illness or other characteristics protected by law. Alexion provides reasonable accommodations to meet the needs of candidates and employees. To begin an interactive dialogue with Alexion regarding an accommodation, please contact [email protected]. Alexion participates in E-Verify.AstraZeneca requires all US employees to be fully vaccinated for COVID-19 but will consider requests for reasonable accommodations as required by applicable law.

What Timken makes possible begins with you. Those who came before us helped land a man on the moon, create the world's infrastructure, and introduce renewable energy alternatives. Now you can join the Timken team to write your own unique story and help drive what's next.A career at Timken means you can have an immediate impact doing Work That Matters to the world- improving the efficiency of today's industrial equipment and preparing for the future of motion on our planet and beyond. New employees can start contributing right away, and there are many opportunities to advance your career at your own pace. Join our global team of 20,000 people in 46 countries, and start helping our customers push the limits of what's possible in their world of motion.Timken Power Systems, Schulz Electric brand, is seekingaMechanicfor the New Haven, CT service center responsiblefor performing general labor, mechanical, and maintenance tasks. Essential Responsibilities: Mechanical Assembleris responsible for the assembly, testing, disassembly andinspection and painting of electric motors Various assembly duties while following customer specifications Ensure the quality of all work sent to the test panel Complete all related paperwork accurately and thoroughly Demonstrate the ability to understand and utilize drawings, sketches and geometric dimensioning, tolerances and repair manuals Providing feedback to engineering on assembly/ test discrepancies, drawing errors, quality errors, etc. in an effort to resolve problems and prevent reoccurrences Ability to work overtime, weekends and holidays when necessary to meet production demands is required Basic Qualifications: Associate must be proficient in multiple craft skills needed to repair and manufacture electrical,mechanical and rotating equipment Proficient use of calipers, micrometers, and dial indicators to measure tolerances as tight as .0005 Must be proficient in the care and handling, installation, adjustment, lubrication and maintenance of anti-friction bearings. Applicant must have both verbal and written communication skills Must have the ability to carry out instructions furnished in written, oral or diagram form Must have mathematical skills with the ability to add, subtract, multiply and divide all units of measure, using whole numbers, common fractions and decimals, along with ability to compute rate, ratio and percent Must be able to effectively present information in one-on-one and small group situations to other employees of the organization Must have a high school diploma or equivalent and 5 years of experience Associate will demonstrate an understanding of and the ability to perform dynamic balancing of rotors and rotating elements All qualified applicants shall be treated equally according to their individual qualifications, abilities, experiences and other employment standards. There will be no discrimination due to gender or gender identity, race, religion, color, national origin, ancestry, age, disability, sexual orientation, veteran/military status or any other basis protected by applicable law. The Timken Company designs a growing portfolio of engineered bearings and industrial motion products that improve the reliability and efficiency of global machinery and equipment to move the world forward. Timken posted $4.5 billion in sales in 2022 and employs more than 20,000 people globally, operating from 46 countries. Why Choose Timken? Over a century of knowledge and innovation A culture of top performance A global, diverse environment Products that contribute to a sustainable world A conviction to improve communities around us Competitive salary and benefits Not Ready To Apply? Stay connected by joining our network and we'll keep you informed about upcoming events and opportunities that match your interests.Talent Community Nearest Major Market: New Haven Nearest Secondary Market: Hartford Job Segment: Maintenance Mechanic, Mechanic, Inspector, Electrical, Manufacturing, Operations, Quality, Engineering

Careers that Change Lives In this exciting role as the Clinical Research Program Manager (CRPM) in the Surgical Robotics Operating Unit , you will be responsible for creating and executing business strategy and influencing internal and external customers to drive business results. This position requires innovative thinking and experience with respect to program strategy and project management for multiple clinical programs, evaluating the safety and effectiveness of new products and / or modifications to existing products. This work is accomplished with minimal oversight, requires frequent contact with internal and external customers, and has significant impact to the business. Many programs are global and will require an understanding of the worldwide landscape.The CRPM will provide global leadership in the development, coordination, and execution of clinical research activities for multiple clinical programs and external research programs. The position may be responsible for all project management activities including the successful execution of clinical milestones in compliance with applicable clinical/regulatory standards, facilitation of effective inter-and intra- departmental relationships, evaluation of new processes and methods, and achievement of multiple Clinical Affairs departmental corporate goals and objectives on time and on budget.We believe that when people from different cultures, genders, and points of view come together, innovation is the result - and everyone wins. Medtronic walks the walk, creating an inclusive culture where you can thrive. To learn more about Inclusion & Diversity at Medtronic Click HereSurgical Robotics employees believe that every patient around the world deserves access to quality care and improved outcomes. Driven by our Mission, we believe that surgical robotics can add value to the healthcare ecosystem, lessen variability, and help more people around the world get better, faster.We're making that exciting future possible - and disrupting one of the biggest and fastest growing markets in healthcare - with a game-changing portfolio of robotic and data & analytics technologies, services, and solutions.A Day in the Life • Develops and implements clinical evidence strategies to obtain timely product approvals form worldwide regulatory bodies.• May be assigned to support new product development representing the clinical function on the Core Team.• Provides leadership for the conduct of clinical studies and for the clinical affairs function as it applies to product approval.• Studies must be scientifically valid, meet all relevant regulatory requirements, and be conducted within ethical guidelines.• The result of the clinical studies must be a fair assessment of the safety and efficacy of the tested product (s) and attainment of product approvals in a timely matter.• Ensures clinical deliverables for regulatory submissions are accurately prepared and comply with regulatory approvals.• Represents the Medtronic Business Unit from clinical research respective within the country / region and also collects feedback from local internal and external customers and authorities.• Builds and maintains a strong network and close relationship with the various internal and external parties.• Leads execution for both local and global studies, manages clinical research projects over all the Medtronic therapies across multiple geographies.• Oversees quality by maintaining compliance, reviewing device complaints, organizing audit preparation and training study teams, reviewing audit reports, and implementing corrective actions.• Oversees the clinical department SOP/DOP review and development, employee training, and associated requirements.• Supports ongoing evidence requirements for products released for commercial use globally. Other Responsibilities: • Autonomy: Manages one or more medium scale, established programs with generally defined program plans and delivery methodologies.• Is accountable for overall program process, performance, and customer satisfaction.• Organizational Impact: Participates in establishing program objectives, timelines, milestones, and budgets.• Develops new policies and procedures that affect program management.• Typically has budget accountability for one or more programs.• Program decisions are generally recommended to higher level management.• Innovation and Complexity: Problems and issues faced are difficult and undefined, and require detailed information gathering, analysis and investigation to understand the problem.• Problems typically impact multiple workstreams, departments or specialties.• Enhances programs management processes to improve program.• Communication and Influence: Communicates and leads meetings with internal and external customers and vendors, conducts briefings to higher level management team.• Influences across functions and businesses while balancing divergent objectives to gain cooperation of other parties on program objectives and execution plans.• Leadership and Talent Management: Leads, directs, and reviews the work of a team of managers, experienced professionals and/or vendors who exercise latitude and independence in their assignments.• Establishes daily tasks necessary for successful program execution.• Not directly responsible for hire or fire decisions and people management.• Represent Clinical Affairs on the Program Core Teams• Interface with regulatory agencies, as appropriate• Provide high quality clinical evidence through study teams• Latitude in decision-making and determining objectives and approaches to critical assignments• Provides clinical strategy for study design development and global evidence collection• Provides management input review and approval of the Clinical Investigational Plan (study protocol), Instructions For Use (IFU), Investigator's Brochure, Report of prior Investigations, Case Report Forms (CRFs), and other appropriate sections of the Investigational Device Exemption (IDE), Clinical Evaluation Reports (CER), Clinical Study Reports (CSRs), and annual reports in consultation with the cross-functional project team, investigators, data management, and biostatistics.• Oversee the evaluation of clinical data/information, writing, and revising of annual, interim, and final reports and clinical sections of Pre-Market Approval (PMA) and Design Dossier submissions.• Oversee quality by maintaining team compliance, reviewing device complaints, reviewing audit reports, and implementing corrective actions• Prepare for potential regulatory inspections in collaboration with the study team and other internal stakeholdersMust Have: Minimum Requirements Bachelors degree required Minimum of 5 years of relevant experience, or advanced degree with a minimum of 3 years of relevant experience Nice to Have • Master's degree in Life Science/Engineering/Public Health degree preferred• 7+ years of experience managing clinical operations and/or programs within Medtronic or medical device industry• Project Management Professional (PMP),Certification as a Lean Six Sigma Black Belt; MP/RMP certification; Project Management Certification (preferably PMI) and/or Green Belt Certification.• Excellent understanding of global clinical compliance• Significant experience with multi-national global clinical trials and/or external research programs• Global regulatory product inspection and preparation experience• Extensive therapeutic disease knowledge and experience in the surgical interventions area• Experience with Quality System Regulation (QSR 21 CFR 820), Canadian Medical Device Regulation (CMDR), EU Medical Device Directive (EU MDD 93/42 EEC), EU MDR (2017/745), and ISO 13485 and 14155About MedtronicTogether, we can change healthcare worldwide. At Medtronic, we push the limits of what technology, therapies and services can do to help alleviate pain, restore health and extend life. We challenge ourselves and each other to make tomorrow better than yesterday. It is what makes this an exciting and rewarding place to be.We want to accelerate and advance our ability to create meaningful innovations - but we will only succeed with the right people on our team. Let's work together to address universal healthcare needs and improve patients' lives. Help us shape the future.Physical Job RequirementsThe physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager, recruiter or local HR to understand the Work Conditions and Physical requirements that may be specific to each role. (ADA-United States of America)

This is what you will do: This position is responsible for leading research, design and execute scientific studies to enable the drug product (DP) process development, characterization, clinical manufacturing, and commercial validation of parenteral/injectable biologic products. Lead and support execution of stability studies, data processing, compiling and presentation of results supporting late-stage clinical activities as well as preparation for PPQ. The candidate will support the development of a variety of manufacturing unit operations including, but not limited to, drug substance (DS) freeze/thaw, compounding/mixing, sterile filtration, drug product filling of vials/syringes, visual inspection, and DS/DP transportation. A general understanding of protein chemistry and/or the ability to run biopharmaceutical assays in a laboratory is preferred. The role will lead manufacturing technology transfer activities in preparation for DS and DP PPQs, including but not limited to sending/receiving site process gap analysis, process FMEAs (failure mode and effects analysis), change control owner/leader, master batch record review, as well as leading at-scale/full scale process development studies, and authoring protocols, and reports. In addition, the candidate will support deviation investigations, change controls, and CAPAs utilizing electronic Quality system. The candidate will also provide clinical and commercial manufacturing site support including but not limited to periodic meetings, action item owner, and as necessary in-person on-site manufacturing support. This position is expected to interact regularly with cross-functional staff from Analytical Sciences & Quality Control, Drug Substance Process Development, Manufacturing Technical Services, Quality Assurance, and/or CMC Regulatory Affairs to support progress of the program and preparation of source documentation supporting BLA. You will be responsible for: Lead the design and execute studies for Alexion pharmaceuticals' clinical drug candidates and commercial products, support tech transfer activities for internal manufacturing and contract manufacturing sites Lead progression of projects with cross functional stakeholders, as well as understand the cross functional implication of project activities and decisions with minimal supervision Prioritizing multiple assigned tasks and projects independently and as part of the team Contribute to the development of strategic project plans for molecules in clinical development Author SOPs, study protocols and technical reports with minimal supervision Participate in cross-functional development teams representing Injectable Drug Product Development Maintain knowledge of current trends in drug product manufacturing processes, manufacturing equipment and single use systems as well as associated global regulatory expectations and scientific principles and theories. Actively participate in department and team meetings including assuming ownership and delivering on assign action items Develop presentations for meetings with internal and external stakeholders with minimal supervision Mentor and train junior Associate Scientists and Engineers regarding drug product development You will need to have: Bachelor's degree in Chemical Engineering, Chemistry, Biochemistry, Pharmaceutical Sciences, or relevant Engineering/Life Sciences field with 7+ years of relevant experience or Master's degree with 6+ years of relevant work experience Self-driven initiative to find resolution for technical challenges Excellent interpersonal, collaborative and communication skills The duties of this role are generally conducted in a lab environment. As is typical of a lab-based role, employees must be able, with or without an accommodation to: lift/carry 15/30 pounds unassisted/assisted; work comfortably in a controlled environment with and around biological, infectious and hazardous materials; gown/degown PPE; use a computer; engage in communications via phone, video and electronic messaging; engage in problem solving and non-linear thought, analysis and dialogue; collaborate with others; maintain general availability during standard business hours. We would prefer for you to have: Scientific and practical knowledge of protein biochemistry and/or drug product process development is preferred Previous experience in biotherapeutics development as well as relevant knowledge of cGMP and Quality expectations for PPQs and BLA is preferred Scientific understanding of protein stability, thermodynamics, mechanism of protein degradation, biotherapeutics drug formulation development and analytical tools used to test formulations is a plus High level proficiency in MS Office software including Word, Excel, Outlook, Visio, and PowerPoint In-person statement for 4 days in the office:When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working give us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of four days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

OFFICE LOCATIONMadison, WI, USA#Li-hybrid#PDNWHO WE AREThe mission of The Nature Conservancy (TNC) is to conserve the lands and waters upon which all life depends. As a science-based organization, we develop innovative, on-the-ground solutions to the world's toughest environmental challenges so that people and nature can thrive. Our work is guided by our values, which include a commitment to diversity and respect for people, communities, and cultures. From a rewarding mission to career development and flexible schedules, there are many reasons to love life #insideTNC. Want to know more? Check out our TNC Talent playlist on YouTube to hear stories from staff or visit Glassdoor.One of TNC's primary goals is to cultivate an inclusive work environment so that employees around the globe have a sense of belonging and feel that their unique contributions are valued. We know we'll only achieve our mission by hiring and engaging a diverse staff that reflects the communities in which we work. Recognizing that people bring talent and skills that have been developed outside the scope of a job, we take a holistic approach to recruitment that considers life experience in addition to the professional requirements listed in our postings. Please apply - we'd love to hear from you. To quote a popular saying at TNC, "you'll join for the mission, and you'll stay for the people."WHAT WE CAN ACHIEVE TOGETHERYour science expertise, communication skills, ability to focus and deliver as a genuine and thoughtful leader, supervisor and team player will help address the global biodiversity and climate crises here in Wisconsin and far beyond.Together, we will deploy science-based projects to achieve conservation outcomes while also informing, supporting and inspiring specific individuals and organizations to take action, and frequently, to change their practices. Ultimately, we seek to transform systems so that people and nature can thrive for the long-term. Scientists at The Nature Conservancy embody our core value of Tangible, Lasting Results.The Wisconsin Director of Conservation Science is a leader in The Nature Conservancy's Wisconsin Business Unit, responsible for integrating an evidence-based, scientific approach for priority applied conservation and policy work. They play a lead role in shaping and implementing TNC's climate action and renewable energy approaches in Wisconsin and the Midwest. They work independently and on teams, with the discipline and perspective to apply expertise and resources selectively to advance top priorities. They ensure that work in Wisconsin integrates with TNC's Midwest Division, North American Region and Global science initiatives.The Wisconsin Director of Conservation Science defines science priorities for TNC in Wisconsin and leads and manages a team to support and improve ongoing projects. They establish the Conservancy as a conservation science partner in the State, serving as the principal science contact to government agencies, other conservation organizations, foundations, the academic community and the Wisconsin Board of Trustees.The Director of Conservation Science develops key partnerships with public and private organizations to identify, resolve and communicate solutions and best practices to identified audiences. They develop scientific methods, analyses, tools, and frameworks that address natural system needs and engage local communities for conservation outcomes. They co-create and facilitate complex and innovative solutions, working with Conservancy colleagues, government agencies, non-profit organizations and community members to benefit natural systems and people. The Wisconsin Director of Conservation Science uses a multi-discipline approach to problem solving and manages an ecology-focused Science and Innovation Team that interfaces with staff, contractors and partners in disciplines including physical, atmospheric and climate sciences, renewable energy, social sciences, economics, technology and engineering. Preferred location Madison, but willing to consider candidates at other locations in Wisconsin. WE'RE LOOKING FOR YOUIf you are a highly collaborative leader with demonstrated standing in the scientific community and a proven track record of outcomes and guiding successful teams, we welcome your application. The Wisconsin Director of Conservation Science will have the opportunity to lead and grow The Nature Conservancy's applied science program capacity and identify opportunities for collaboration with a wide range of conservation partners working together to tackle the climate and biodiversity crises for the benefit of people and nature. This role will require your ongoing commitment to embedding diversity, equity, inclusion, and justice in your work and the work of the organization.A typical week will include projects like: Co-creating and deploying climate adaptation and resiliency projects Evaluating, implementing and communicating about an equitable clean energy transition, natural solutions for carbon capture and nature-based solutions to help nature and communities adapt to climate change Helping shape climate messages and coaching colleagues on strategic climate engagement Promoting the Conservancy's Resilient and Connected Network tool to select audiences Helping draft TNC's public comments and positions on conservation priorities Partnering with colleagues and partners on science/academic grants and publications Serving on advisory teams such as Wisconsin Initiative on Climate Change Impacts Determining the Conservancy's role in public agency planning effortsWHAT YOU'LL BRING BA/BS degree and 7 years' experience in conservation practice or related field or equivalent combination of education and experience. Experience communicating complex issues to non-scientists, including donors Experience managing complex or multiple projects, including managing finances and coordinating the work of other professionals and partners. Supervisory experience, including motivating, leading, setting objectives and managing performance. Experience in partnership development with non-profit partners, community groups and/or government agencies. Experience negotiating.DESIRED QUALIFICATIONS Masters or Ph.D. and 7-10 years' experience in conservation practice or equivalent combination of education and experience. Expertise and knowledge of current trends and practices in Midwestern aquatic or terrestrial systems or climate change. Demonstrated experience communicating, influencing, developing and implementing conservation science policy and plans. Ability to develop practical applications of scientific concepts and technical innovations for conservation purposes. Communicating clearly via written, spoken, and graphical means in English and other relevant languages, including a track-record of peer-reviewed publications. Experience with developing a diversity of collaborations with a strong emphasis and proven experience with diversity, equity, inclusion, and justice. Politically savvy. WHAT WE BRINGSince 1951, TNC has been doing work you can believe in. Through grassroots action, we have grown from a small non-profit into one of the most effective and wide-reaching environmental organizations in the world. Thanks to more than 1 million members, over 400 scientists, and the dedicated efforts of our diverse staff and partners, we impact conservation around the world! TNC offers a competitive, comprehensive benefits package including health care benefits, flexible spending accounts, a 401(k) plan with an 8% employer match, parental leave, accrued paid time off, life insurance, disability coverage, employee assistance program, other life and work well-being benefits. Learn more about our benefits on our Culture Tab on nature.org/careers.We're proud to offer a flexible work environment that supports of the health and well-being of the people we employ.SALARY INFORMATIONThe starting pay range for a candidate selected for this position is generally within the range of $79,500-$97,100 for annual base salary. This range only applies to candidates whose country of employment is the USA. Where a successful candidate's actual pay will fall within this range will be based on a variety of factors, including, for example, the candidate's location, qualifications, specific skills, and experience. Please note countries outside the USA would have a different pay range in the local currency based on the local labor market, and not tied to USA pay or ranges. Your geographic location will be confirmed during the recruitment.APPLY NOWTo apply for job ID 54515, submit your materials online by using the Apply Now button at https://careers.nature.org/. Need help applying? Visit our recruitment page or contact [email protected] Nature Conservancy is an Equal Opportunity Employer. Our commitment to diversity includes the recognition that our conservation mission is best advanced by the leadership and contributions of people of diverse backgrounds, beliefs and culture. Recruiting and mentoring staff to create an inclusive organization that reflects our global character is a priority and we encourage applicants from all cultures, races, colors, religions, sexes, national or regional origins, ages, disability status, sexual orientation, gender identity, military, protected veteran status or other status protected by law.The successful applicant must meet the requirements of The Nature Conservancy's background screening process.Do you have military experience? Visit our U.S. Military Skills Translator to match your military experience with our current job openings!TNC is committed to offering accommodations for qualified individuals with disabilities and disabled veterans in our job application process. If you need assistance or an accommodation due to a disability, please send a note to [email protected] with Request for Accommodation in the subject line.An attractive salary and benefits package is part of TNC's value proposition to our employees. TNC strives to provide competitive pay and bases salaries on the geographic location of the role committing to being equitable across groups and providing hiring salary ranges when possible. Since we support flexible and remote work for our employees, many positions have a flexible location within countries where we're registered as a Non-government Organization and established as an employer. This may mean we're unable to provide a hiring salary range in the posting for some of our positions. However, candidates invited to be part of our interview process will be provided their location specific range upon request.PDN-9b041bbc-68e6-42c7-b3e7-d79b3a2d5a55

Job ID: 497279Tilcon Connecticut Inc., a CRH company, has played a vital role in building infrastructure around our state, serving the market from 23 locations throughout Connecticut. As a leading supplier of quality crushed stone, hot mix asphalt, and ready mix concrete, Tilcon Connecticut has supported the construction of superior roads, buildings and bridges. The most respected name in the construction industry, from the quarry to the road, Tilcon Connecticut does it all!Are you looking for opportunities and benefits of a large corporation with a small company feel? Then Tilcon Connecticut Inc. and CRH is the company for you! If you're up for a rewarding challenge, we invite you to take the first step and apply today!PRIMARY RESPONSIBILITIES This skilled position involves maintenance of all company equipment. PRINCIPLE ACCOUNTABILITIES Analyzes malfunctions and repairs, rebuilds, and maintains construction equipment such as trucks, trailers, cranes, paving machines, motor graders, trench-digging machines, bulldozers, pumps, compressors and pneumatic tools. Operates and inspects machines or equipment to diagnose defects. Dismantles and reassembles equipment, using hoists and hand tools. Examines parts for damage or excessive wear, using micrometers and gauges. Replaces defective engines and subassemblies, such as transmissions. Tests overhauled equipment to ensure operating efficiency. QUALIFICATIONS Thorough mechanical knowledge of equipment and vehicles. Ability to follow verbal and written instructions. Ability to perform all job duties in a safe and efficient manner. Minimum of 2 year's experience mechanical/PM maintenance of construction and off highway equipment. CDL Class B with Airbrake, Tanker and Hazmat endorsements. PERSONAL PROTECTIVE EQUIPMENTEmployees are required to wear personal protective equipment in designated operations and construction areas as outlined by OSHA, MSHA and state agencies. Protective equipment that may be required, but not limited to, for this position: Hard hat, safety glasses, face shield, welding helmet, reinforced toed shoes, hand protection, respirator, air monitor and reflective safety vest.PHYSICAL DEMANDSThe physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.While performing the duties of this job, the employee is regularly required to sit and use hands to finger, handle or feel objects, tools, or controls. The employee is frequently required to talk or hear. The employee is required to stand, walk, reach with hands and arms, climb or balance, stoop, kneel, crouch or crawl and taste or smell. Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception and the ability to adjust to focus, and drive a vehicle.The employee must occasionally lift and/or move up to 100 pounds.Continuous Frequently Occasionally NotApplicable Bend X Kneel X Squat X Climb X Stand X Walk X Sit X Reach X Drive X Fine motor X Repetitive Motion X Right X Left X This position requires an employee to lift:Continuous Frequently Occasionally NotApplicable 0 - 10 lbs X 10 - 25 lbs X 25 - 50 lbs X 50 - 100 lbs X WORK ENVIRONMENTThe work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.While performing the duties of this job, the employee frequently works near moving mechanical parts and is occasionally exposed to wet and/or humid conditions and heat. The employee frequently works outside and has exposure to some vibration.The noise level in the work environment is usually moderate.This is a first shift days position. Some Saturday work will be required at certain points.Continuous Frequently Occasionally Not Applicable Hot Weather X Cold Weather X Wet Weather X Exposed to Noise X Exposed to High Heat X Moving Equipment X Working with Others X What CRH Offers You Highly competitive base pay Comprehensive medical, dental and disability benefits programs Group retirement savings program Health and wellness programs A diverse and inclusive culture that values opportunity for growth, development, and internal promotion About CRHCRH has a long and proud heritage. We are a collection of hundreds of family businesses, regional companies and large enterprises that together form the CRH family. CRH operates in a decentralized, diversified structure that allows you to work in a small company environment while having the career opportunities of large international organization.If you're up for a rewarding challenge, we invite you to take the first step and apply today! Once you click apply now, you will be brought to our official employment application. Please complete your online profile and it will be sent to the hiring manager. Our system allows you to view and track your status 24 hours a day. Thank you for your interest! Tilcon Connecticut Inc., a CRH Company, is an Affirmative Action and Equal Opportunity Employer.EOE/Vet/Disability--If you want to know more, please click on this link. Date: May 13, 2024 Nearest Major Market: New Haven Nearest Secondary Market: Hartford Job Segment: Maintenance Mechanic, Mechanic, Construction, Welding, Manufacturing, Operations, Engineering

Job ID: 493473Tilcon Connecticut Inc., a CRH company, has played a vital role in building infrastructure around our state, serving the market from 23 locations throughout Connecticut. As a leading supplier of quality crushed stone, hot mix asphalt, and ready mix concrete, Tilcon Connecticut has supported the construction of superior roads, buildings and bridges. The most respected name in the construction industry, from the quarry to the road, Tilcon Connecticut does it all!Are you looking for opportunities and benefits of a large corporation with a small company feel? Then Tilcon Connecticut Inc. and CRH is the company for you! If you're up for a rewarding challenge, we invite you to take the first step and apply today!Position Overview Tilcon Connecticut has an opening for an experienced third shift utility person in our North Branford quarry. As a utility person, the selected candidate will be required to work in a team environment with other co-workers and managers. Our core values are safety, quality and integrity in everything we do. All Tilcon Connecticut employees are expected to partner with associates and management of Tilcon Connecticut Inc. to coordinate, support, and actively promote our safety process. The utility person will report directly to the quarry superintendent and will comply with mandatory safety requirements and other functions of the quarry team.Operating Engineers union wages and benefits.Key Responsibilities (Essential Duties and Functions) Safely and efficiently operate maintenance equipment and report any problems to your manager in a timely fashion. Perform maintenance and housekeeping on quarry equipment as needed, using ladders to access platforms, and landings. Heavy lifting required (75 to 100 lbs.) Shovel sand, stone and wet materials daily. Will be working at considerable heights. Properly follow all company policies and OSHA / MSHA regulations for safe working procedures and environment. Follow direction of foreperson with regard to daily tasks and expectations for each specific project or jobsite. Perform daily pre-and-post inspections with appropriate documentation in compliance with company policies. Display a professional and courteous attitude to co-workers, supervisors and the general public at all times. Report to work at the designated start time and stay through end of shift. Be able to work overtime when required. Must be able to have a flexible schedule to coincide with business need. Be willing to work outdoors in extreme temperatures, both hot and cold. Strictly adhere to safety requirements and procedures. Have the willingness to work in a team environment and assist co-workers or supervisors with other duties as required. Wear personal protective equipment (PPE) in designated operations and production areas as stated by OSHA and / or MSHA. Perform other duties as assigned. Qualifications To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. Education/Experience Minimum high school diploma or general education degree (GED) required. Trade / Mechanical education preferred. Maintenance / Mechanical experience preferred. Mechanical ability Work Requirements Good mechanical ability Welding and torch cutting is an asset but not required Pass pre-employment drug screen and criminal background check Pass a re-employment "Fit for Work" physical Physical Requirements The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.While performing the duties of this job, the employee is regularly required to talk and hear. The employee is required to sit, walk and stand for periods of time. The employee is required to use a computer for extended periods of time. Specific vision abilities required by this job include close vision, distance vision, peripheral vision, depth perception and the ability to adjust to focus.Continuous: Sit, drive Frequently: Bend, climb, stand, walk, reach, fine motor, repetitive motion, right, left Occasionally: Kneel, squatThis position requires an employee to lift:Continuous: Frequently: 0-10 lbs.; 10-25 lbs.; 25-50 lbs. Occasionally: Work Environment The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.While performing the duties of this job, the employee occasionally works near moving mechanical parts and is occasionally exposed to wet and/or humid conditions and heat. The employee frequently works outside and has exposure to some vibration. The noise level in the work environment is usually moderate.Continuous: Moving equipment, working with others Frequently: Hot weather, cold weather, exposed to noise Occasionally: Wet weather, exposed to high heatThe statements included in this job description are not intended to be all-inclusive. They represent typical elements and criteria necessary to successfully perform the job. Other duties may be assigned as required. Requirements for this job are subject to modification by the Company and its designees, and reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.COMPANY INFORMATION Tilcon Connecticut Inc. is a leading supplier of quality crushed stone, hot mix asphalt and ready mix concrete products throughout the state of Connecticut. We also provide heavy and highway construction, site work, and paving services for state and local road, bridge, and highway projects. Tilcon Connecticut Inc. and Oldcastle Materials is a great place to grow. If you're up for a rewarding challenge, we invite you to take the first step and apply today! Thank you for your interest in expanding your career with Tilcon Connecticut Inc. and Oldcastle Materials. Oldcastle has a long and proud heritage as one of North America's largest corporations. We are a proud reflection of the hundreds of family businesses, local and regional companies and mid to large sized enterprises that together form the Oldcastle family. Oldcastle operates with a decentralized, diversified structure, letting you work in a small company environment while having the career opportunities of a large enterprise.Oldcastle Materials is the leading vertically integrated supplier of aggregates, asphalt, ready mix concrete and paving services with 1400 locations nationwide. From coast to coast, Oldcastle Materials delivers quality, dependable results to customers ranging from federal agencies to small construction companies. Our culture is special as well. Our most valued asset is our people, and Talent Management is an ongoing process that helps us to identify, develop, and leverage more than 18,000 employees. Whether we are safely paving miles of interstate, building two thousand-foot-long bridges or building roads in national parks, Oldcastle Materials' continued investment in people, performance, and communities has positioned us as an industry leader. What CRH Offers You Highly competitive base pay Comprehensive medical, dental and disability benefits programs Group retirement savings program Health and wellness programs A diverse and inclusive culture that values opportunity for growth, development, and internal promotion About CRHCRH has a long and proud heritage. We are a collection of hundreds of family businesses, regional companies and large enterprises that together form the CRH family. CRH operates in a decentralized, diversified structure that allows you to work in a small company environment while having the career opportunities of large international organization.If you're up for a rewarding challenge, we invite you to take the first step and apply today! Once you click apply now, you will be brought to our official employment application. Please complete your online profile and it will be sent to the hiring manager. Our system allows you to view and track your status 24 hours a day. Thank you for your interest! Tilcon Connecticut Inc., a CRH Company, is an Affirmative Action and Equal Opportunity Employer.EOE/Vet/Disability--If you want to know more, please click on this link. Date: May 16, 2024 Nearest Major Market: New Haven Nearest Secondary Market: Hartford Job Segment: Architecture, Construction, Welding, Engineering, Manufacturing