Scientist Salary in Cambridge, MA

Company DescriptionEurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.In 2020, Eurofins generated total revenues of EUR € 5.4 billion, and has been among the best performing stocks in Europe over the past 20 years.Job DescriptionThe individual will execute relevant protocols to purify therapeutic oligonucleotides suitable for downstream in vivo studies. We are looking for a scientist that possesses a strong background in chemistry or related scientific fields, hand-on experience in oligonucleotide analytical techniques, along with a willingness to learn and collaborate in a fast-paced environment.Responsibilities:Implement relevant purification protocols to ensure delivery of therapeutic oligonucleotides suitable for in vivo studies.Develop new methods as needed to improve purification parameters of oligonucleotides & conjugates.Author and maintain documentation such as laboratory notebooks and scientific reports.Contribute to the general safety, maintenance, and logistics of a synthetic laboratory.Follow and embrace all the company's safety policies.Perform other laboratory and/or company duties as assigned.QualificationsB.S. or M.S in Chemistry or related scientific field with 1 - 2 years relevant experienceDemonstrate excellent working knowledge of purification technology as it relates to therapeutic oligonucleotides (IEX and RP, FPLC)Demonstrate excellent working knowledge of analytical instrumentation and method development as it pertains to oligonucleotides (HPLC & LCMS)Anion exchange chromatographyAdditional InformationPosition is full-time, Monday - Friday, 8-hour shift.Candidates currently living within a commutable distance of Cambridge, MA are encouraged to apply.Excellent full time benefits including comprehensive medical coverage, dental, and vision options.Life and disability insurance401(k) with company matchPaid vacation and holidaysEurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

Harvard UniversityDescription: 21-Mar-2024Research ScientistFaculty of Arts and Sciences 65316BRJob SummaryIn the Department of Molecular and Cellular Biology at Harvard University, we research and teach how the collective behavior of molecules and cells forms the basis of life. We are driven by a passion for discovery and value collaborative approaches to scientific inquiry where connections between people fuel interdisciplinary science and break boundaries across varied experimental systems.The Denic lab Research Scientist position available would work alongside graduate students and postdoctoral researchers, performing research in the area of protein folding, quality control, and homeostasis.Position DescriptionIndependently designs and conducts complex scientific experiments utilizing advanced laboratory techniques and equipment to achieve the major goals of the lab’s research projectsEstablishes protocols and develops new laboratory techniquesProcesses, organizes, summarizes, and analyzes data, reporting experiment results using a variety of scientific, word processing,spreadsheet or statistical software applications or program platforms.May train and oversee the work of others in laboratory techniques and procedures.Assists with laboratory maintenance such as maintaining and/orpurchasing equipment and supplies, working with vendors and undertaking special projects as required.Contributes to lab goals by undertaking other duties as required.Prepares and collaborates on articles for submission to scientific journals and publicationsBasic QualificationsMaster’s degree required5+ years working in abiological research setting.Additional Qualifications and Skills10+ years working in a biological research setting is preferred.Doctorate preferred.Excellent oral and written communication skillsAbility to oversee complex projects through to completionAbility to exercise discretion and independent judgmentAdditional InformationWe are unable to provide visa sponsorship for this positionAll formal offers will be made by FAS Human ResourcesWork Format DetailsThis position is based primarily on-campus, in Massachusetts. This may include in-person during emergency situations (if applicable). Additional details will be discussed during the interview process. BenefitsWe invite you to visit Harvard's Total Rewards website (https://hr.harvard.edu/totalrewards) to learn more about our outstanding benefits package, which may include: Paid Time Off: 3-4 weeks of accrued vacation time per year (3 weeks for support staff and 4 weeks for administrative/professional staff), 12 accrued sick days per year, 12.5 holidays plus a Winter Recess in December/January, 3 personal days per year (prorated based on date of hire), and up to 12 weeks of paid leave for new parents who are primary care givers. Health and Welfare: Comprehensive medical, dental, and vision benefits, disability and life insurance programs, along with voluntary benefits. Most coverage begins as of your start date. Work/Life and Wellness: Child and elder/adult care resources including on campus childcare centers, Employee Assistance Program, and wellness programs related to stress management, nutrition, meditation, and more. Retirement: University-funded retirement plan with contributions from 5% to 15% of eligible compensation, based on age and earnings with full vesting after 3 years of service. Tuition Assistance Program: Competitive program including $40 per class at the Harvard Extension School and reduced tuition through other participating Harvard graduate schools.Tuition Reimbursement: Program that provides 75% to 90% reimbursement up to $5,250 per calendar year for eligible courses taken at other accredited institutions. Professional Development: Programs and classes at little or no cost, including through the Harvard Center for Workplace Development and LinkedIn Learning.Commuting and Transportation: Various commuter options handled through the Parking Office, including discounted parking, half-priced public transportation passes and pre-tax transit passes, biking benefits, and more. Harvard Facilities Access, Discounts and Perks: Access to Harvard athletic and fitness facilities, libraries, campus events, credit union, and more, as well as discounts to various types of services (legal, financial, etc.) and cultural and leisure activities throughout metro-Boston.Job FunctionResearch Department Office LocationUSA - MA - Cambridge Job CodeRS0157 Researcher III Natural Science Work FormatOn-Site Sub-UnitSciences Salary Grade057DepartmentMolecular & Cellular BiologyUnion00 - Non Union, Exempt or Temporary Time StatusFull-time Pre-Employment ScreeningEducation, IdentitySchedule35 hours per weekCommitment to Equity, Diversity, Inclusion, and BelongingHarvard University views equity, diversity, inclusion, and belonging as the pathway to achieving inclusive excellence and fostering a campus culture where everyone can thrive. We strive to create a community that draws upon the widest possible pool of talent to unify excellence and diversity while fully embracing individuals from varied backgrounds, cultures, races, identities, life experiences, perspectives, beliefs, and values.EEO StatementWe are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law.LinkedIn Recruiter Tag (for internal use only)#LI-KO1 PI238477912

About Us: As a not-for-profit organization, Mass General Brigham is committed to supporting patient care, research, teaching, and service to the community by leading innovation across our system. Founded by Brigham and Women's Hospital and Massachusetts General Hospital, Mass General Brigham supports a complete continuum of care including community and specialty hospitals, a managed care organization, a physician network, community health centers, home care and other health-related entities. Several of our hospitals are teaching affiliates of Harvard Medical School, and our system is a national leader in biomedical research.We're focused on a people-first culture for our system's patients and our professional family. That's why we provide our employees with more ways to achieve their potential. Mass General Brigham is committed to aligning our employees' personal aspirations with projects that match their capabilities and creating a culture that empowers our managers to become trusted mentors. We support each member of our team to own their personal development-and we recognize success at every step.Our employees use the Mass General Brigham values to govern decisions, actions and behaviors. These values guide how we get our work done: Patients, Affordability, Accountability & Service Commitment, Decisiveness, Innovation & Thoughtful Risk; and how we treat each other: Diversity & Inclusion, Integrity & Respect, Learning, Continuous Improvement & Personal Growth, Teamwork & Collaboration.GENERAL SUMMARY / OVERVIEW: The Gene and Cell Therapy Institute (GCTI) is a newly created system-wide Institute under Mass General Brigham. The Institute will foster a world-class gene and cell therapy program that will leverage ongoing, groundbreaking scientific research efforts across the MGB system. The mission of GCTI is to bring together the community of MGB investigators which can utilize gene and cell therapy platforms to achieve their scientific and clinical goals and improve the health of patients. The Institute will differentiate itself by harnessing the exceptional strengths of clinician scientists, the large and unique patient population, and major discoveries throughout the hospital system to propel MGB as the leader in Gene & Cell therapies. The Abudayyeh-Gootenberg Gene Editing lab at the Mass General Brigham Gene and Cell Therapy Institute is seeking a highly organized and dynamic individual to serve as a manager and principal scientist for a new Gene Editing and Perturbation (GEP) core housed at the GCTI. This unique role provides an opportunity to be a part of a team contributing to the forefront of technology development in gene therapy, cell therapy, and aging research and supporting the entire MGB ecosystem's research and development in the gene editing and genomic perturbation space.This position is designed for a motivated and skilled individual who will be instrumental in managing the GEP's operations. The GEP is a new model, established by the GCTI, to assist researchers both across MGB and external groups with performing gene editing experiments and pooled genetic screens. Successful candidates will play a pivotal role in establishing the core, hiring additional members to assist with core activities, setting up initial services, and working with potential investigators in the MGB ecosystem. Additionally, there is the opportunity to engage in cutting-edge research and collaborations, including but not limited to publishing results, assisting with pre-clinical asset development, and eventually in scale up of reagents for clinical trials. We are looking for someone who thrives in a fast-paced, innovative environment and is passionate about supporting science that makes a difference. The ideal candidate will be highly organized, possess exceptional planning skills, and demonstrate a strong curiosity about the work. Furthermore, existing experience with genome editing, CRISPR, lentiviral preparation, and pooled screening is strongly preferred.PRINCIPAL DUTIES AND RESPONSIBILITIES:Core Management • Oversee daily operations of the GEP core, ensuring efficient workflow and compliance with safety regulations.• Establish systems and infrastructure for accepting orders and billing customers.• Ensure proper and timely production of requested samples.• Setting up initial lab services and activities.• Assist clients with critical know-how for designing and debugging experiments.• Recruiting additional core staff as needed.Scientific Support• Purify lentiviral libraries for pooled genetic screening.• Transduce cell lines with libraries.• Harvest DNA and analyze NGS results of pooled screens.• Perform cell sorting as needed to read out screens.• Handle primary cell lines for genome editing experiments.• Design and test guide RNAs for CRISPR technologies, including nucleases, CRISPRi, base editing, and prime editing.• Delivery genome editing reagents to cell lines and primary cells using diverse delivery technologies, including DNA lipofection, mRNA delivery, viral transduction, and electroporation.Qualifications • PhD in n a relevant scientific discipline.• Experience with genome editing and CRISPR technologies.• Experience with genome-wide screening.• Prior experience in lab management and leadership is helpful.• Strong organizational skills and the ability to multitask effectively.• Excellent communication skills, both written and verbal.• Proficiency in office and lab software, including Microsoft Office Suite and laboratory information management systems (LIMS).• Knowledge of laboratory safety and compliance regulations.• Demonstrated ability to work independently as well as part of a team.SKILLS/ ABILITIES/ COMPETENCIES:• High degree of computer literacy• Sound analytical and organizational skills.• Requires good oral and written communication skills.• Must be able to logically and effectively structure tasks and set priorities.• Ability to identify problems in the lab and trouble-shoot solutions.• Independent drive and motivationEEO Statement Mass General Brigham is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.

Company DescriptionEurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins works with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.Eurofins is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. Eurofins is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. The Group also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.In over just 30 years, Eurofins has grown from one laboratory in Nantes, France to 55,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 50 countries. Eurofins offers a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.In 2020, Eurofins generated total revenues of EUR € 5.4 billion, and has been among the best performing stocks in Europe over the past 20 years.Job DescriptionResponsibilitiesContributes as part of a small team of scientists towards the development/optimization, and qualification/verification of analytical methods to support synthetic molecules analytical development.Applies in-depth knowledge of concepts and applications to fit-for-purpose methods development.Provided analytical support for process and formulation development related works.Reviews and interprets data then communicates results to relevant members.Identifies, troubleshoots, and implements resolutions to technical problems/issues.Conducts work in compliance with cGMP/GLP, safety and regulatory requirements.Writing technical reports for functional areaIndependently plans and designs experiments and operations within expertise.Able to clarify requests and provide suggestions and put data into context.Works with departmental and/or other function members to execute on assignments, under limited supervision.Learn new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.Effectively communicates complex data/decisions within department.Contributes significantly to project related lab works within functional area.Coordinates work with members in the teamQualificationsWorking knowledge of analytical techniques with experience using multiple techniques (LC, GC, Dissolution, Karl Fisher, spectroscopic instruments, etc.) for synthetic molecules.Basic understanding of industry practices and standards.Experiences on method development and validation for synthetic molecule productsStrong computer, scientific, and organizational skills.Analytical and Problem Solving Skills - Able to troubleshoot critical issues or problems and determine causes and possible solutions using appropriate informationAbility to work well in a team environmentCommunication Skills - Able to expresses oneself clearly and concisely within teamOrganization - Exercises good time management and prioritization skills and is able to successfully manage multiple tasks simultaneouslyAuthorization to work in the United States indefinitely without restriction or sponsorshipEducation and ExperienceAssociates degree in chemistry, biology, pharmacy, engineering, or related pharmaceutical science with 7+ years relevant industry experienceBachelor's degree in chemistry, biology, pharmacy, engineering, or related pharmaceutical science with 4+ years relevant industry experienceMaster's degree in chemistry, biology, pharmacy, engineering, or related pharmaceutical science with 2+ years relevant industry experienceAdditional InformationPosition is full-time, Monday - Friday. 8:00-5:00pm are the hours.Candidates currently living within a commutable distance of Cambridge, MA are encouraged to apply.Excellent full time benefits including comprehensive medical coverage, dental, and vision options.Life and disability insurance401(k) with company matchPaid vacation and holidaysEurofins is aM/F, Disabled, and Veteran Equal Employment Opportunity and Affirmative Action employer.

The Role:The successful candidate will partner with a multidisciplinary team to develop internal capabilities and perform screens to discover and characterize antigen variants with improved surface expression and thermal stability. The goal is to use library construction and verification coupled with mammalian display to enable campaigns for multiple targets of interest. Successful lead generation will allow for subsequent testing in pre-clinical models and subsequently in the clinic. The position offers significant scientific growth opportunities in several areas including vaccine development, infectious disease biology, protein engineering and automation.Responsibilities:You will work in close collaboration with research leadership and a team of peers to identify and prioritize targets for screening. Success will require a collaborative and proactive approach with a clear focus on effective team work. Excellent laboratory and organizational skills combined with insightful and decisive data analysis will be required to ensure that program team deadlines are consistently reached. Presentation in program team and departmental meetings will be required to communicate results and recommendations to stakeholders. Further responsibilities include report and protocol writing, reagent generation and archiving, equipment onboarding, inventory maintenance and data archiving (ELN/LIMS).Skill Set: Experience with both library screening and mammalian display are essential and ideally include: molecular biology methods for multiple library generation strategies (including key PCR methods for library construction in addition to rigorous cloning methods for efficient vector library assembly and verification, familiar with random mutagenesis and DNA extraction technique), lentivirus production and transduction, mammalian cell culture, FACS and NGS sequencing methods and associated data analysis techniques. Additional skills to support downstream characterization as needed would be beneficial and could include: protein expression and purification using FPLC systems and biophysical characterization methods (SEC-MALS, DSF, and biosensor techniques including BLI and SPR.Here's What You'll Do: Collaborate with bioinformatics team to translate library design concepts into experimental strategy with associated timelines.Collaborate with wet lab team members to further develop screening strategy and assign responsibilities to ensure timely progress balanced with other activities.Perform library generation and cloning, perform cell staining, use FACS to isolate clones with improved expression, prepare DNA samples for NGS, coordinate with NGS team to acquire and analyze data, archive all data in accessible formats.Collaborate with manager to integrate experimental design and outcomes for presentation to team and program members, make recommendations based on data and program team feedback.Utilize an ELN to capture experimental results and participate in LIMS integration.Assist in reagent ordering and inventory in addition to procurement and maintenance of laboratory equipment.Here's What You'll Bring to the Table:Exceptional Ph.D. in immunology, bacteriology, virology, molecular biology, biochemistry or biophysics ideally with industry experience.Outstanding laboratory experience and knowledge in various library construction and screening workflows, experimental design, data analysis and ability to transition hypotheses into data and scientific insights.Knowledge of mRNA biotechnology, bacteriology, virology, immunology, protein structure and vaccine design is a plus.Candidates will be curious in exploring new paths for drug discovery, bold in proposing creative experimental designs and ideas, will work collaboratively with multifunctional teams and be relentless in pursuing successful outcomes.Candidates must possess excellent data management and verbal/written communication skills, have excellent track record in experimental performance, evaluate and process data, present results in a clear, concise and timely manner, and assist with the preparation of final written reports.Ability to work independently and as part of a team in a highly dynamic, fast-paced, matrixed environment with evolving priorities.Ability to collaborate with colleagues to achieve scientific and career goals aligned with business objectives.Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:Highly competitive and inclusive medical, dental and vision coverage optionsFlexible Spending Accounts for medical expenses and dependent care expensesLifestyle Spending Account funds to help you engage in personal enrichment and self-care activitiesFamily care benefits, including subsidized back-up care options and on-demand tutoringFree premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipmentAdoption and family-planning benefitsDedicated care coordination support for our LGBTQ+ communityGenerous paid time off, including:• Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafterGenerous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning toolsModerna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit optionsComplimentary concierge service including home services research, travel booking, and entertainment requestsFree parking or subsidized commuter passesLocation-specific perks and extras! About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.Moderna is a smoke-free, alcohol-free and drug-free work environment.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. (EEO/AAP Employer) #LI-JW2-

The Role:Moderna Infectious Disease Research is seeking a talented, creative, and motivated scientist with experience in computational protein design, bioinformatics and vaccine design, to be part of the Antigen Design and Selection team. The Scientist will be part of a highly collaborative, multi-disciplinary, and fast-paced team that is translating Moderna's mRNA technology into an exceptionally broad portfolio of vaccines and therapeutics against infectious diseases. The Scientist will employ their expertise in computational protein structure prediction and design, and vaccinology, to assist the design and evaluation of novel vaccines and therapeutics that can be delivered via Moderna's mRNA-LNP technology platform. In this work, the Scientist will collaborate with other cross-functional teams within Moderna and with external groups to advance and develop novel mRNA-based vaccine candidates. Located in Cambridge, MA, the Scientist should be outstanding in their fields of expertise, a collaborative team member and excellent communicator, and should be excited to work with cutting edge mRNA technology in the advancement of vaccines and therapeutics for human health.This is a unique opportunity to work in an innovative environment on a truly transformative infectious diseases platform.Here's What You'll Do: Use state of the art modeling and design software and algorithms to investigate protein structures and sequences from viral and bacterial pathogens and to design new vaccine antigens and therapeutics to be tested in vitro and in vivo by other team members.Develop a deep biological understanding of each vaccine or therapeutic target through literature and data review and discussions with colleagues, formulate design requirements based on this understanding, and incorporate these requirements into the computational design processCollaborate with team members to formulate experimental plans to evaluate designed antigens and therapeuticsCollaborate with team members to plan in vitro evolution compaigns to refine computationally designed antigens and therapeutics and to analyze the results of such campaigns.Collaborate with team members to analyze biophysical, structural, and immunological data related to evaluation of designed antigens and therapeutics, and develop improved designs based on the data from the previous iteration.Propose novel vaccine and therapeutic targets aligned with Moderna's scientific strategy and capabilities.Work closely with cross-functional teams across the Moderna ecosystem, collaborators and CROs to progress candidates from discovery through IND-enabling studies.Maintain expertise in the fields of computational protein structural modeling and design, AI methods for design and analysis, and infectious disease vaccines; thoroughly keeping up to date with literature, attending relevant meetings, and liaising with external experts in the field.Manage multiple projects and interactions with supporting functions in parallel.Provide scientific and technical support for multidisciplinary project teams.Prepare documents and present strategy, results, project updates, and summaries.Here's What You'll Bring to the Table:Exceptional PhD with expertise in computational protein design, bioinformatics, and protein biochemistry and biophysics.Experience with Rosetta and state-of-the-art machine-learning methods for protein design, including but not limited to RFDiffusion, ProteinMPNN, and AlphaFold2.Proficiency in Linux-based systems, scripting languages (e.g. Python/R/Perl), high throughput computing architectures such as AWS, and a good working knowledge of relevant data analysis and visualization packages.Track record of publications and presentations in the fields of protein design and vaccine development.Strong critical thinking and problem-solving skills.Proven ability to interpret complex data and present conclusions in a clear and understandable way to a broad audience.The ability to work independently and collaboratively in a cross-functional work environment.Positive team building and teamwork skills, willing to give and receive constructive feedbackExcellent written, presentation and interpersonal communication skills; ability to influence and collaborate in a team environment.Candidate will be curious in exploring new paths for vaccine and therapeutic discovery, bold in proposing creative designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes.Experience in wet lab molecular biology and protein biochemistry, including protein production and purification in mammalian and bacterial cells, is desirable.Experience in biophysical analysis to determine protein melting temperature and solution multimeric state, and experience is desirable.Experience in assessing protein-protein interactions by SPR and/or Octet is desirable.Experience in design and functional evaluation of antibodies is desirable.Understanding of immunology, particularly adaptive immune responses by B and T cells, would be a plus.Knowledge of virology or bacteriology would be a plus.Experience in carrying out and interpreting FACS experiments would be a plus.Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:Highly competitive and inclusive medical, dental and vision coverage optionsFlexible Spending Accounts for medical expenses and dependent care expensesLifestyle Spending Account funds to help you engage in personal enrichment and self-care activitiesFamily care benefits, including subsidized back-up care options and on-demand tutoringFree premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipmentAdoption and family-planning benefitsDedicated care coordination support for our LGBTQ+ communityGenerous paid time off, including:• Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafterGenerous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning toolsModerna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit optionsComplimentary concierge service including home services research, travel booking, and entertainment requestsFree parking or subsidized commuter passesLocation-specific perks and extras! About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.Moderna is a smoke-free, alcohol-free and drug-free work environment.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. (EEO/AAP Employer) #LI-KF1-

Job DescriptionBiogen is seeking a qualified candidate to fill a Scientist II or Senior Scientist position within its Small Molecule Development organization. This individual will work with other scientists to develop drug product formulations including pediatric formulations to support small molecule formulation development from pre-clinical through commercialization. This position is ideally suited for someone with a background and broad knowledge in solutions and suspensions and other formulation platforms suitable for pediatrics, knowledge in the characterization of such formulations and the ability to use material-sparing tools to create robust manufacturing process.The successful candidate will design, execute, and document formulation and process development studies for all kinds of drug candidates especially for those that are poorly soluble and be able to present technical information at appropriate level to stakeholders.This is an on-site position at our headquarters in Cambridge, MA. Responsibilities include (but are not limited to):Develop both oral liquid and solid dosage forms for clinical use and commercialization.Help develop strategy and formulation development plans for pediatric formulations.Actively engage CMC teams as the Formulation lead and contribute to deliverables and participate in cross-functional technical review and troubleshooting.Propose, and advocate for project timelines; be the primary point of contact for technology transfer to inform planning, communication; inform and/or influence the selection of external partners and external innovation.Execute and oversee technical transfers, scale up and clinical manufacture at internal drug-product GMP facilities and at CMOs.Apply materials science principles and techniques to develop, characterize, and implement processes and next generation technologies to solve technical challenges and clearly communicate the value of the scientific initiative.Champion and lead innovation in process modeling, data analysis and machine learning applicable to drug product development.Provide support, as needed, to clinical drug product manufacturing through process capability analysis and product impact/risk assessments for process changes/improvements and non-conformance investigations.Author/review guideline documents, technical protocols, reports, product impact and risk assessments, and drug product sections in IND, IMPD and NDA filingsQualificationsRequired SkillsPh.D. in Pharmaceutical Science, Materials Science, Chemical or Mechanical Engineering, or related field with 2 - 5 years of relevant industry experience ORM.S degree with 6+ years of experience in Pharmaceutical Science, Materials Science, Chemical or Mechanical Engineering, or related field ORBachelor's degree with 8+ years of experience in Pharmaceutical Science, Materials Science, Chemical or Mechanical Engineering, or related field.Preferred SkillsPh.D. degree with hands-on experience in unit operations involved in the manufacture of oral liquid and solid dosages.Good knowledge of small molecule formulation techniques and concepts of drug product process developmentExperience/knowledge in formulation development for a range of dosage forms including solids and liquids from early to late phase.Strong problem-solving and troubleshooting skills, strong capabilities in experimental design and execution, as well ability to work independently are essential.Strong verbal and written communication skills, strong interpersonal skills and the ability to serve as a team member/leader in an environment where individual initiative, collaboration and accountability are valued.Proven skills and ability to work collaboratively with both internal and external partners.Additional InformationWhy Biogen?Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients' lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.PDN-9bc75f3a-dcf4-45d8-b8d6-38fb919a5850

The RoleModerna is seeking a statistical scientist deeply passionate about empirical research in drug discovery and early development. You will lead and execute computational strategies for drug design, develop novel methodologies, and partner with scientists to advance Moderna's platform technology.This position requires a strong foundation in data analysis and applied statistics. You will contribute to critical decision-making across the life cycle of drug discovery and development. This position has significant visibility and potential for growth in a dynamic organization.Here's What You'll DoLead computational investigations into the impact of novel formulations on biology. Partner with cross-functional teams to develop principled design of experiment strategies (e.g., adaptive designs, optimal designs), statistical models and computational methods. Design and carry out data analysis strategies (normalization, statistical inference) for biophysical measurements and bioassays (e.g., ELISA, amplicon-seq, mass spec). Explore and build novel statistical models or machine learning methods to advance our platform technology.Collaborate with bioinformatic engineers and develop tools to enable data democratization.Independently manage multiple concurrent, fast-paced projects across Moderna's research ecosystem. Partner with wet-lab and dry-lab scientists. Contribute to our culture of best data practices and statistical excellence. Conduct educational seminars on statistics and computational methods.Here's What You'll Need (Minimum Qualifications)Ph.D. in Statistics, Biostatistics, or related quantitative discipline5+ years of relevant academia or industry experience (post PhD) is requiredEstablish records working with cross-functional teams (e.g., publications, work experiences)Strong coding skills with R and PythonExcellent written and oral communication skillsHere's What You'll Bring to the Table (Preferred Qualifications)Establish record of analyzing multiple data types and building principled statistical modelsEstablish expertise in one of the following:High-dimensional biological data analysis and methodsEmpirical Bayesian methodsReinforcement learning, active learningExperience with Python, version control tools (git, GitHub), high performance computing and AWS cloud computing platformPositive team building and team work skills: innate ability to influence, lead and inspire people, within function and beyond functional/company boundariesCandidate will be curious in exploring new path for drug discovery, bold in proposing creative experimental designs and statistical methods. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes.Moderna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:Highly competitive and inclusive medical, dental and vision coverage optionsFlexible Spending Accounts for medical expenses and dependent care expensesLifestyle Spending Account funds to help you engage in personal enrichment and self-care activitiesFamily care benefits, including subsidized back-up care options and on-demand tutoringFree premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipmentAdoption and family-planning benefitsDedicated care coordination support for our LGBTQ+ communityGenerous paid time off, including:• Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafterGenerous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning toolsModerna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit optionsComplimentary concierge service including home services research, travel booking, and entertainment requestsFree parking or subsidized commuter passesLocation-specific perks and extras! About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.Moderna is a smoke-free, alcohol-free and drug-free work environment.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. (EEO/AAP Employer) #LI-KF1-

The Role:Moderna is seeking a highly motivated bioinformatician with solid training in cancer genomics data analysis to work as part of a highly collaborative, multi-disciplinary, and fast-paced team. The primary focus for this position is to curate and evaluate cancer specific genomic aberrations and immune evasion mechanisms, translate public and proprietary information into useful training data to help develop bioinformatics algorithms to incorporate this information in individualized neoantigen therapy (INT) programs. The successful candidate will work closely with computational biologists, immunologists, and translational scientists in Oncology Research to support PCV discovery research and clinical development.Here's What You'll DoLeading scientific evaluations of different genomics data processing pipelines, especially on somatic variant calling methods.Evaluating different NGS technology and workflows.Explore, evaluate, and prioritize external and internal biological assay data to improve INT bioinformatics algorithm.Collaborating with discovery and translational biologists to support INT research and clinical development.Building an innovative team that is specialized in cancer genomics data analysis and pipelining.Here's What You'll Need (Minimum Qualifications)Ph.D. in a computational discipline, such Bioinformatics, Computational Biology, Physics, Computer Science, or StatisticsDemonstrated scientific research experience with high throughput genomics dataExtensive experience with Python and R, high-performance computing, and AWSOutstanding communication skills (verbal and written)Here's What You'll Bring to the Table (Preferred Qualifications)Prior experience developing genomics data processing methods, ideally in the cancer spaceStrong problem-solving skills and a results-oriented mindsetDemonstrated cross-functional collaboration with multidisciplinary teams Curious about exploring a new pathway for drug discoveryBe bold in proposing and delivering on creative experimental designs and ideasPrior experience with staging and sequencing projects independently and presenting results to non-technical stakeholdersCollaborate effectively and manage multiple projects in a dynamic, cross-functional matrix environmentModerna is pleased to provide you and your family with a comprehensive and innovative suite of benefits, including:Highly competitive and inclusive medical, dental and vision coverage optionsFlexible Spending Accounts for medical expenses and dependent care expensesLifestyle Spending Account funds to help you engage in personal enrichment and self-care activitiesFamily care benefits, including subsidized back-up care options and on-demand tutoringFree premium access to fitness, nutrition, and mindfulness classes Exclusive preferred pricing on Peloton fitness equipmentAdoption and family-planning benefitsDedicated care coordination support for our LGBTQ+ communityGenerous paid time off, including:• Vacation, sick time and holidays• Volunteer time to participate within your community• Discretionary year-end shutdown• Paid sabbatical after 5 years; every 3 years thereafterGenerous Paid Leave offerings, including 18 weeks of 100% paid parental leave for all new parents 401k match and Financial Planning toolsModerna-paid Life, LTD and STD insurance coverages, as well as voluntary benefit optionsComplimentary concierge service including home services research, travel booking, and entertainment requestsFree parking or subsidized commuter passesLocation-specific perks and extras! About ModernaSince our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world. By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.As we build our company, we have always believed an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute and make a meaningful impact.If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.Moderna is a smoke-free, alcohol-free and drug-free work environment.Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We're focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should contact the Accommodations team at [email protected]. (EEO/AAP Employer) #LI-KF1-

Job DescriptionAbout This Role Biogen is presently looking to fill a Scientist II position within its Anti-Sense Oligonucleotide (ASO) Formulation and Drug Product Development group. The candidate will be responsible for formulation and process development activities of oligonucleotide drug product programs to support Biogen's growing pipeline. Candidate is expected to work collaboratively in a matrix environment with other members of the technical development team. The candidate must be motivated and innovative with exceptional analytical and communication skills.This is a hybrid role to be based at our headquarters in Cambridge, MA. What You'll Do Design and execution of laboratory experiments supporting process development for the continuous improvement of Biogen's oligonucleotide manufacturing platformsExecution of formulation and process development study protocols, stability and product characterization studiesDevelopment and on-site support of cGMP drug product manufacturing processesClosely interfacing with chemical synthesis, purification and analytical groups to support oligonucleotide manufacturing platformsCoordinating pre-clinical test article supply with Research scientistsWriting protocols, performing data analysis, and authoring reportsAuthoring and reviewing all necessary SOPs, protocols, and study reports, as well as common technical documentation for regulatory submissionsCapable of working independently, eager to learn new concepts, and bring a can-do attitudePresenting scientific data to technical teams, ability to manage several projects simultaneously, and excellent communication skills, both written and oral.QualificationsWho You Are You have general knowledge of parenteral drug product development and manufacturing. You will be part a dynamic oligonucleotide drug product development group consist of scientists and engineers. You will be working closely with the Pharma Process Development and Regulatory CMC team as well as R&D, Manufacturing and Quality teams to support development activities of Biogen oligonucleotide programs. You have passion for learning and proactive attitude to drive success in your new role. You enjoy and thrive in a fast-paced team/matrix environment as well as working independently to manage priorities and maintain project timeline. Your dedication to excellence and your ability to adapt to a dynamic, matrixed organization will be key assets in achieving our collective goals.Education Requirements: Ph.D. in Pharmaceutical Sciences, Biochemical Engineering, Chemical Engineering or related field with 0 - 4 years' experience in pharmaceutical or biotech settings. (including Ph.D. candidates graduating in Spring-Summer, 2024)OR M.S. degree with 4+ to 6 years of relevant experienceOR B.S. degree with 6+ to 8 years of relevant experienceRequired Skills: Familiar with pharmaceutical development.Demonstrated experience with sterile drug product development and parenteral formulations preferably with hands-on experience with oligonucleotides.Understanding of drug product manufacturing process operations such as mixing, sterile filtration, extractable/leachable assessments, and container filling/closing.Experience in analytical and characterization methods such as chromatography, spectroscopy, calorimetry and particle analysis technologies.Preferred Skills:Knowledge of statistical software, design or experiment programming and general visualization of sophisticated data sets is a plus.Prior experience working in a biopharmaceutical product development environment and familiarity with GMP guidelines is preferred.Experience in developing and analyzing drug delivery systems, such as polymeric and lipid nanoparticles is a plus.Additional InformationWhy Biogen?Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients' lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.At Biogen, we are committed to building on our culture of inclusion and belonging that reflects the communities where we operate and the patients we serve. We know that diverse backgrounds, cultures, and perspectives make us a stronger and more innovative company, and we are focused on building teams where every employee feels empowered and inspired. Read on to learn more about our DE&I efforts.All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.PDN-9bcb6470-d96b-4eef-ad8f-2bbf73542bfd